Lecturer at Swami Atmanand Government English Medium School, Ahiwara, Durg,India
Profile:
Scopus
Education:
🎓 Doctor of Philosophy (Ph.D.) in Chemistry
University: Pt. Ravishankar Shukla University, Raipur, (C.G.), India
Date: 10, July 2018
Mentor: Prof. Rama Pande
🥇 Master of Science (M.Sc.) in Chemistry
School: School of Studies in Chemistry, Pt. Ravishankar Shukla University, Raipur, (C.G.), India
Percentage: 74.38% (Gold Medalist)
Year: 2012
📜 Life Memberships
- Chemical Research Society of India (LM 1736)
- Fellow of Indian Chemical Society
🎓 Bachelor of Education (B.Ed.)
College: M. J College Bhilai
Subjects: All Compulsory with Physical and Biological Science
Percentage: 79.88%
University: Pt. Ravishankar Shukla University, Raipur, (C.G.), India
Year: 2013
🎓 Bachelor of Science (B.Sc.)
College: G. D. Rungta College of Science & Technology, Bhilai
Subjects: Chemistry, Botany, Biotechnology, Foundation Course
Percentage: 70.88%
University: Pt. Ravishankar Shukla University, Raipur, (C.G.), India
Year: 2010
Professional Experience:
🎓 Academic and Professional Experience
Active INSPIRE Research Scholar
- Institution: Pt. Ravishankar Shukla University, Raipur (C.G.), India
- Duration: 2013-2018
- Roles: Conducted doctoral research and taught courses
📚 Guest Lecturer
- Institution: Pt. Ravishankar Shukla University, Raipur (C.G.), India
- Duration: 2019-2020
🔬 Postgraduate Teacher (PGT) in Chemistry
- School: D.A.V. ISPAT School, Sector-2, Bhilai, Chhattisgarh, India
- Current Role
📝 CBSE Observer
- Role: Served as CBSE observer in two schools
🔬 Research Focus:
📚 Thesis Title:
“Studies on Hydroxamic Acid Metal Complexes as Nucleic Acid Binder and Enzymatic Inhibitors”
Mentor: Prof. Rama Pande
🔍 Research Overview:
The thesis investigates the biological properties of Hydroxamic acid-Metal complexes, focusing on their binding with nucleic acids (DNA/RNA) and enzymatic inhibition. This pioneering study utilized various techniques including UV-Visible Spectroscopy, Fluorescence Spectroscopy, Viscosity measurements, and Molecular Docking with Hex and AutoDock software.
🧬 Key Findings:
- Nucleic Acid Binding:
- Five Hydroxamic acid-Metal complexes were studied for their nucleic acid binding parameters.
- Four complexes were identified as Minor groove binders and one as a Major groove binder.
- Molecular Docking:
- Molecular docking analyses (using Hex and AutoDock) complemented experimental results.
- All five complexes successfully docked into the enzyme HDAC 8, demonstrating efficient binding.
- Cytotoxicity Studies:
- Cytotoxicity against MCF-7 Breast Cancer cells was conducted.
- The Copper-Hydroxamic acid complex emerged as the most effective molecule.
🔬 Techniques Used:
- Spectroscopy: UV-Visible, Fluorescence
- Viscosity Techniques
- Molecular Docking: Hex, AutoDock
- Cytotoxicity Assays
🧪 Implications:
The research provides crucial insights into the binding modes of Hydroxamic acid-Metal complexes with nucleic acids and enzymes. It highlights the potential of these complexes, particularly the Copper-Hydroxamic acid complex, for further in-vivo analysis and therapeutic applications.
Technical Proficiency:
• Professional Techniques (UV-Visible Spectroscopy, Fluorescence
Spectroscopy, Rp-HPLC, NMR, Fluorescence Microscope, Gel
Electrophoresis, FT-IR, and Viscosity)
• Computational Based Theoretical Analysis Molecular Docking Analysis
• High presentation skills
• Computer Efficient (Office and Research based software)
🏆 Awards and Achievements:
🎓 INSPIRE Fellow
- Ph.D. financially assisted by the Department of Science & Technology, New Delhi, India
🥇 M.Sc. Merit List – 1st Position (2012)
- Awarded 4 Gold Medals in the year 2013
🏅 National Young Scientist Awardee
- Indian Council of Chemists, Pune, India (2016)
🏅 State Young Scientist Awardee
- Chhattisgarh Young Scientist Awardee, Bhilai, Chhattisgarh, India (2017)
Citations:
- 🔢 Citations: 186 citations by 161 documents
- 📑 Publications: 20 documents
- 📈 h-index: 8
Publication Top Notes:
Engineering the future with hydrogels: advancements in energy storage devices and biomedical technologies
Authors: Sharma, A.K., Sharma, R., Pani, B., Sarkar, A., Tripathi, M.
Journal: New Journal of Chemistry, 2024, 48(23), pp. 10347–10369
In-vitro and in-silico analysis and antitumor studies of novel Cu(II) and V(V) complexes of N-p-Tolylbenzohydroxamic acid
Authors: Tripathi, M., Thakur, Y., Syed, R., Verma, B., Pande, R.
Journal: International Journal of Biological Macromolecules, 2024, 268, 131768
Nucleic acids: Components, nomenclature, types, and protection method
Authors: Tripathi, M., Sarkar, A., Mahilang, M.
Book: Handbook of Biomolecules: Fundamentals, Properties and Applications, 2023, pp. 57–76
Hydrogels and their combination with lipids and nucleotides
Authors: Tripathi, M., Sharma, R., Hussain, A., Sharma, A.K., Sarkar, A.
Book: Sustainable Hydrogels: Synthesis, Properties, and Applications, 2023, pp. 471–487
Erratum to: Copper(ii) complexes supported by modified azo-based ligands: Nucleic acid binding and molecular docking studies (Open Chem. (2022) 20:1(505-516) DOI: 10.1515/chem-2022-0164)
Authors: Tripathi, M., Asatkar, A.K., Antony, S., Alqahtani, M.S., Syed, R.
Journal: Open Chemistry, 2022, 20(1), pp. 1084
Copper(ii) complexes supported by modified azo-based ligands: Nucleic acid binding and molecular docking studies
Authors: Tripathi, M., Asatkar, A.K., Antony, S., Alqahtani, M.S., Syed, R.
Journal: Open Chemistry, 2022, 20(1), pp. 505–516
N-hydroxypyrazine-2-carboxamide as a new and green corrosion inhibitor for mild steel in acidic medium: experimental, surface morphological and theoretical approach
Authors: Dewangan, Y., Verma, D.K., Berdimurodov, E., Mishra, V.K., Kumar, P.A.
Journal: Journal of Adhesion Science and Technology, 2022, 36(23-24), pp. 2644–2664
In vitro investigation of biophysical interactions between Ag(I) complexes of bis(methyl)(thia/selena)salen and ct-DNA via multi-spectroscopic, physicochemical and molecular docking methods along with cytotoxicity study
Authors: Tripathi, M., Syed, R., Stalin, A., Pande, R., Asatkar, A.K.
Journal: Luminescence, 2021, 36(5), pp. 1277–1284
Assessment and evaluation of ambient pm2.5 in relation to its health effects in mineral-based coal-fired areas
Authors: Pervez, S., Sahu, R.K., Tripathi, M., Deb, M.K., Pervez, Y.F.
Journal: Geofizika, 2020, 37(1), pp. 67–90
Spatiotemporal variability and source apportionment of the ionic components of groundwater of a mineral-rich tribal belt in Bastar, India
Authors: Dugga, P., Pervez, S., Tripathi, M., Siddiqui, M.N.
Journal: Groundwater for Sustainable Development, 2020, 10, 100356