Andrey Popatanasov | Neuroscience | Best Researcher Award

Dr. Andrey Popatanasov | Neuroscience | Best Researcher Award 

Research Assistant, at Institute of Neurobiology, Bulgarian Academy of Sciences, Bulgaria.

Andrey Popatanasov is a dedicated Research Assistant at the Institute of Neurobiology, Bulgarian Academy of Sciences (BAS). His academic journey is distinguished by a multidisciplinary approach: he holds Bachelor’s degrees in Psychology, Physics, and Biology, complemented by Master’s degrees in Clinical Psychology, Medical Physics, and Molecular Biology. Currently, he is pursuing a PhD in Human and Animal Physiology, expected to be conferred this year. Professionally, Popatanasov has been affiliated with various institutes under BAS, contributing to integrative research that bridges the gap between basic science and its application to human well-being. His work aims to advance our understanding of neurobiological mechanisms and their implications for human health.

Professional Profile

Scopus

ORCID

Education

Popatanasov’s educational foundation is both broad and deep, reflecting his commitment to understanding complex biological systems. He earned Bachelor’s degrees in Psychology, Physics, and Biology, providing him with a diverse scientific perspective. Building on this, he completed Master’s degrees in Clinical Psychology, Medical Physics, and Molecular Biology, each aligning with his evolving research interests. Currently, he is finalizing his PhD in Human and Animal Physiology, which will further enhance his expertise in neurobiology. This extensive academic background equips him to approach research questions from multiple disciplinary angles, fostering innovative solutions to complex problems in neuroscience and related fields.

Experience

Throughout his academic and professional career, Popatanasov has gained substantial experience in research and academia. He has been involved in various research projects at institutes of the Bulgarian Academy of Sciences, where he applied his multidisciplinary training to investigate neurobiological phenomena. Currently, as a Research Assistant at the Institute of Neurobiology, he contributes to studies that explore the molecular and physiological aspects of the nervous system. His role encompasses experimental design, data analysis, and dissemination of findings, all aimed at advancing scientific knowledge and its practical applications in medicine and healthcare.

Research Interests

Popatanasov’s research interests lie at the intersection of neuroscience, psychology, biology, and physics. He investigates the molecular mechanisms underlying cognitive, affective, and pro-social behaviors, particularly in pathological conditions. His work includes in silico and in vitro studies on ligand interactions with brain biomolecules, as well as the impact of electromagnetic radiation from quantum generators on living and non-living matter. Additionally, he explores the relationship between language complexity and brain development in children with disabilities. These interdisciplinary pursuits aim to uncover fundamental insights into brain function and inform therapeutic strategies for various neurological disorders.

Awards

While specific awards are not detailed in the provided information, Popatanasov’s contributions to neuroscience and interdisciplinary research are noteworthy. His work has been recognized through his involvement in peer-reviewed publications and editorial roles, indicating a respected standing within the scientific community. His dedication to advancing knowledge in neurobiology and related fields reflects a commitment to excellence in research and its application to human health.

Top Noted Publications

Popatanasov has co-authored several significant publications in reputable scientific journals. One notable article is “New Insights into the Cytoarchitecture of the Rat Spinal Trigeminal Nucleus,” published in the Proceedings of the Bulgarian Academy of Sciences in July 2024. This study provides detailed histological analysis of the spinal trigeminal nucleus, contributing to the understanding of sensory processing in the trigeminal system. Another key publication is “Expression of Neurotrophic Factors and Their Receptors in the Rat Spinal Trigeminal Nucleus,” also in the Proceedings of the Bulgarian Academy of Sciences, published in September 2024. This research examines the role of neurotrophic factors in neuronal differentiation and survival, with implications for pain modulation and neuroplasticity. These publications underscore Popatanasov’s active engagement in advancing neurobiological research.proceedings.bas.bg+2proceedings.bas.bg+2proceedings.bas.bg+2proceedings.bas.bg

Publications with Hyperlinks and Citation Information

🧠 1. New Insights into the Cytoarchitecture of the Rat Spinal Trigeminal Nucleus

DOI: 10.7546/CRABS.2024.07.11

This study delves into the structural organization of the spinal trigeminal nucleus (SpV), a pivotal relay station for processing sensory information from the face, head, and oral cavity. Historically considered a continuous structure, it was revealed to be subdivided into three distinct subnuclei: oral, interpolar, and caudal. Utilizing histological techniques, the researchers identified unique cytoarchitectural features characteristic of each subnucleus, providing insights into the spatial distribution and density of neuronal populations across the rostrocaudal extent of the SpV. These findings enhance the understanding of the neural circuitry underlying sensory processing in the trigeminal system and may have implications for the diagnosis and treatment of disorders involving altered trigeminal function. proceedings.bas.bg+1proceedings.bas.bg+1

🧬 2. Expression of Neurotrophic Factors and Their Receptors in the Rat Spinal Trigeminal Nucleus

DOI: 10.7546/CRABS.2024.09.15

In this follow-up study, the authors investigated the expression of neurotrophic factors—nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and glial-derived neurotrophic factor (GDNF)—and their corresponding receptors in the rat SpV. Using primary antibodies against these neurotrophic factors and their receptors, the researchers found immunoreactive cells scattered along the entire length of the nucleus in all three subnuclei. Notably, the majority of spinal trigeminal neurons were intensely immunostained for all the neurotrophic factors examined and were richly endowed with their Trk receptors. The study also observed regional variations in the expression levels of these factors and receptors within the subnuclei. Given that these neurotrophic factors are involved in mechanisms of central sensitization in trigeminal nociceptive pathways, the findings suggest that neurotrophins may contribute to a better understanding of the fundamental mechanisms of orofacial pain. proceedings.bas.bg

Conclusion

Andrey Popatanasov is a highly interdisciplinary researcher with a solid academic and professional foundation. His efforts to integrate diverse scientific domains (psychology, neuroscience, physics, biology) are commendable. He has made meaningful contributions to both theoretical and applied research, especially in brain science, cognitive behavior, and molecular biology.

Dr Alexandros Kanellopoulos | Neuroscience | Best Researcher Award

Dr Alexandros Kanellopoulos Neuroscience | Best ResearcherAward  🏆

Principal Scientist of Cognitive Health at DSM-Firmenich, RD Innovation
Switzerland🎓

Alexandros Kanellopoulos is a seasoned Innovation Leader, Principal Scientist, and Clinical Director with over 20 years of expertise in Neuroscience, Metabolism, Early Life Nutrition (ELN), and Medical Nutrition. He has successfully led multidisciplinary teams, pioneered product innovations, and authored more than 20 high-impact publications. With 7 patents to his name, Alexandros excels in transforming scientific research into tangible solutions that meet market needs.

Professional Profile 

Education

Alexandros Kanellopoulos holds a Ph.D. in Neuroscience from Kapodistrian University, Greece (2008-2013), where his research focused on neurodevelopmental disorders. Prior to this, he completed his M.Sc. in Molecular Medicine (Neuroscience) at the same university (2005-2007), gaining advanced expertise in neuroscience and molecular biology. His academic foundation was established with a B.Sc. in Molecular Biology and Genetics from Dimocritus University of Thrace, Greece (2000-2005), where he developed a strong background in genetics and molecular biology.

Work Experience

In his current role as Global Principal Scientist & Clinical Director at DSM-Firmenich (2023-Present), Alexandros oversees scientific activities, driving innovation in dietary supplements and medical nutrition. Prior to this, he worked as an R&D Innovation Scientist and Project Manager at Nestle SA (2022-2023), leading the development of brain health products for Early Life Nutrition. In 2023, he also held the position of Medical, Scientific & Regulatory Affairs Manager at Nestle Nutrition, focusing on market communication and regulatory compliance. Alexandros previously served as Group Leader, Early Life Brain Metabolism at the University of Lausanne (2020-2022) and as Senior Scientist in Early Life Neuroscience (2016-2020), where he pioneered research in neurodevelopmental disorders.

Skills 

Alexandros is highly skilled in Innovation & Product Development, leading projects from concept to market. He is an expert in Clinical Research & Protocol Design, managing complex preclinical and clinical trials. His ability to lead multidisciplinary teams and drive Cross-functional Collaboration is complemented by his talent for Stakeholder Engagement & Market Alignment, ensuring alignment between research innovations and market needs. His Strategic Thinking, Problem-solving, and Emotional Intelligence are key to his success in high-impact research and business projects.

Awards & Honors

Throughout his career, Alexandros has earned more than 15 research awards, securing CHF 2.5 million in research funding. He has been awarded 7 patents as an inventor, reflecting his contributions to innovation in neuroscience and nutrition. In addition, he has delivered over 40 invited presentations at international conferences, establishing himself as a respected thought leader in his field.

 Membership 

Alexandros contributes to the scientific community as a Reviewer for leading neuroscience journals and serves as an Editor in scientific publications, ensuring the dissemination of high-quality research.

Teaching Experience

Alexandros is also an experienced educator, having delivered lectures in Neuroscience and Medical Sciences at the University of Lausanne and Kapodistrian University, Athens. In his academic roles, he has mentored over 20 junior scientists, fostering the next generation of researchers and innovators.

Research Focus

Alexandros’ research centers on Early Life Nutrition and its role in brain development. He is particularly focused on Neurodevelopmental Disorders such as Autism and Fragile X Syndrome. His work on Brain Energy Metabolism and Mitochondrial Function provides insights into neurotransmission and social behavior. Alexandros has also designed Preclinical and Clinical Research aimed at developing nutritional solutions to address these complex medical challenges.

Publications : 

  • Activation of the 5-HT1A Receptor by Eltoprazine Restores Mitochondrial and Motor Deficits in a Drosophila Model of Fragile X Syndrome
    🧠 International Journal of Molecular Sciences – 2024
    DOI: 10.3390/ijms25168787
  • Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits
    🧬 Cell – 2020
    DOI: 10.1016/j.cell.2020.02.044
  • Conserved Tao Kinase Activity Regulates Dendritic Arborization, Cytoskeletal Dynamics, and Sensory Function in Drosophila
    🔬 The Journal of Neuroscience – 2020
    DOI: 10.1523/jneurosci.1846-19.2020
  • Domain-Specific Cognitive Impairments in Humans and Flies With Reduced CYFIP1 Dosage
    🧩 Biological Psychiatry – 2019
    DOI: 10.1016/j.biopsych.2019.04.008
  • SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse
    🧠 Neuron – 2019
    DOI: 10.1016/j.neuron.2019.05.002
  • Mitochondrial Dysfunction in Autism Spectrum Disorder: Clinical Features and Perspectives
    🧠 Current Opinion in Neurobiology – 2017
    DOI: 10.1016/j.conb.2017.05.018
  • Autism Spectrum Disorders: Translating Human Deficits into Mouse Behavior
    🐁 Neurobiology of Learning and Memory – 2015
    DOI: 10.1016/j.nlm.2015.07.013
  • Learning and Behavioral Deficits Associated with the Absence of the Fragile X Mental Retardation Protein: What a Fly and Mouse Model Can Teach Us
    🧠 Learning & Memory (Cold Spring Harbor, N.Y.) – 2014
    DOI: 10.1101/lm.035956.114
  • Learning and Memory Deficits Resulting from Reduction of the Fragile X Mental Retardation Protein: A Metabotropic Glutamate Receptor-Mediated Inhibition of cAMP Signaling in Drosophila
    🧠 The Journal of Neuroscience – 2012
    DOI: 10.1523/JNEUROSCI.1347-12.2012
  • Selective Serotonin Reuptake Inhibitors for the Treatment of Hypersensitive Esophagus: A Randomized, Double-blind, Placebo-controlled Study
    💊 The American Journal of Gastroenterology – 2011
    DOI: 10.1038/ajg.2011.179