Assist. Prof. Dr. Nastaran Zamani | Exercise – Appetite – Obesity | Best Researcher Award

Dr. Nastaran Zamani is a distinguished Iranian neuroscientist and Assistant Professor in the Department of Biology at Payame Noor University, Tehran. With a research career grounded in neurophysiology and Alzheimer’s disease models, she has made valuable contributions to understanding the effects of neuroprotective agents like memantine, vitamin D, folic acid, and DHA on cognitive function. Her expertise spans from electrophysiological recordings of hippocampal neurons to behavioral studies in rodent models. Dr. Zamani has actively collaborated with renowned researchers and co-authored over 20 peer-reviewed articles published in leading journals in neuroscience, physiology, and pharmacology. Her work bridges cellular neurobiology and therapeutic research, reflecting an interdisciplinary approach. Dr. Zamani is also known for her participation in national and international scientific congresses. Through her teaching and mentoring roles, she fosters academic growth and promotes scientific inquiry among students and young researchers in Iran. Her commitment to neuroscience research and education continues to inspire many in the field.

Professional Profile

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Education

Dr. Nastaran Zamani earned her Ph.D. in Animal Physiology from Shahid Chamran University of Ahvaz in 2019, with a doctoral thesis focused on the electrophysiological and behavioral effects of memantine and DHA on hippocampal CA1 neurons and spatial memory in Alzheimer’s disease rat models, under the supervision of Prof. Ahmad Ali Moazedi. She completed her MSc in Animal Physiology from Razi University, Kermanshah, in 2004, where her thesis explored the hematological effects of sodium nitrate in mice, co-supervised by Dr. Syrus Shamili and Dr. Syrus Ghobadi. Her academic foundation was built at the University of Isfahan, where she received her BSc in Biology with a focus on Animal Sciences in 1999. Her education reflects a consistent and deep interest in the physiological and biochemical mechanisms underlying cognitive and neurodegenerative disorders, forming the basis of her current research in neuroscience and therapeutic interventions for Alzheimer’s disease and related neurological conditions.

Experience

Dr. Zamani began her academic career as a faculty instructor in the Department of Biology at Payame Noor University from 2011 to 2019. Since 2019, she has held the position of Assistant Professor in the same department. She has over a decade of teaching experience, mentoring undergraduate and graduate students in physiology, neurobiology, and experimental research techniques. Her research focuses on Alzheimer’s disease models, involving electrophysiology, behavioral neuroscience, and pharmacological interventions. Dr. Zamani has presented her findings in more than ten national and international conferences and has authored over 20 peer-reviewed journal articles in neuroscience and physiology. In addition to teaching and research, she has participated in various academic development workshops on molecular biology, drug delivery, data analysis using MATLAB, and scientific writing. Her continuous contributions to neuroscience research and education have strengthened her role as a dedicated academic professional in the Iranian scientific community.

Research Interests

Dr. Zamani’s research centers on the neurophysiological and therapeutic mechanisms underlying Alzheimer’s disease, with a primary focus on hippocampal CA1 neuron activity, memory, and learning. She explores the pharmacological effects of memantine, folic acid, vitamin B12, DHA, and vitamin D in rodent models of neurodegeneration, using electrophysiological recordings and behavioral assessments such as maze tests. Her investigations examine how these compounds influence spatial learning, memory deficits, neuroinflammation, and oxidative stress in Alzheimer’s models. She has expanded her research to include studies on motor coordination, depression, anxiety, and thermal dysregulation related to neurological disorders, as well as broader physiological effects of exercise and natural antioxidants. Her interdisciplinary approach integrates neuroscience, pharmacology, and physiology, supported by collaborations with international researchers and active engagement in congresses and workshops. By bridging cellular mechanisms and therapeutic strategies, Dr. Zamani’s work contributes significantly to preclinical efforts targeting Alzheimer’s disease and cognitive disorders.

Awards

While formal award titles are not explicitly listed, Dr. Nastaran Zamani’s consistent scholarly productivity and academic recognition are evident through her extensive peer-reviewed publications, conference participations, and workshop invitations. She has been selected to present at prestigious neuroscience congresses, such as the Congress of Basic and Clinical Neuroscience, and has contributed to multiple multidisciplinary international collaborations, demonstrating her recognition within the academic community. Her research contributions to Alzheimer’s disease models have earned her collaborative roles in high-impact studies published in journals like Frontiers in Physiology, Molecular and Cellular Biochemistry, and Cytotherapy. She has also participated in professional development programs hosted by Tehran University of Medical Sciences, Elsevier Research Academy, and the International Brain Research Organization, further reflecting her ongoing commitment to academic excellence. Dr. Zamani’s profile highlights the high regard she holds among peers and institutions for her active role in advancing neurophysiological research in Iran and beyond.

Conclusion:

• Transplanted neural-like cells improve memory and Alzheimer-like pathology in a rat model
  E Hoveizi, T Mohammadi, AA Moazedi, N Zamani, A Eskandary
  Cytotherapy 20 (7), 964-973
• Respiratory issues in patients with multiple sclerosis as a risk factor during SARS-CoV-2 infection: a potential role for exercise
  O Razi, AM Teixeira, B Tartibian, N Zamani, B Knechtle
  Molecular and cellular biochemistry 478 (7), 1533-1559
• Thermal dysregulation in patients with multiple sclerosis during SARS-CoV-2 infection. The potential therapeutic role of exercise
  O Razi, B Tartibian, AM Teixeira, N Zamani, K Govindasamy, K Suzuki, …
  Multiple Sclerosis and Related Disorders 59, 103557
• Walking exercise and lower-body blood flow restriction: Effects on systemic inflammation, lipid profiles and hematological indices in overweight middle-aged males
  O Razi, M Mohammadi, N Zamani, AC Hackney, C Tourny, S Zouita, …
  Research in Sports Medicine 30 (1), 41-49
• Multimodal benefits of exercise in patients with multiple sclerosis and COVID-19
  O Razi, B Tartibian, I Laher, K Govindasamy, N Zamani, …
  Frontiers in Physiology 13, 783251
• Effect of memantine on spatial learning and memory in electrical leisions model of nucleus basalis magnocellularis: animal model of Alzheimer’s disease
  PBM Zamani N, Moazedi AA, Afarinesh Khaki MR
  J Gorgan Univ Med Sci 20 (1), 43-50
• Effects of Memantine on the Spontaneous Firing Frequency of Hippocampal CA1 Pyramidal Neurons in Intact and Alzheimer Rat Model: An Electrophysiological Study
  N Zamani, AA Moazedi, MR Afarinesh Khaki, M Pourmehdi Boroujeni
  Basic and Clinical Neuroscience 13 (5), 661-674
• The effects of vitamin B12 on spatial learning and memory in adult male rats model of Alzheimer’s disease
  N Zamani, AA Moazedi, A Eskandary
  Journal of Isfahan Medical School 35 (463), 1949-1955
• The Synergist Effects of Folic Acid and Vitamin B12 on Spatial Memory in Adult Male Rat Model of Alzheimer’s Disease
  A Eskandary, AA Moazedi, N Zamani
  Journal of Rafsanjan University of Medical Sciences 16 (10), 925-938
• The effects of co-administration of memantine and vitamin d on spatial learning and memory impairment in adult male rats model of Alzheimer’s disease
  N Zamani, AA Moazedi
  Journal of Arak University of Medical Sciences 22 (6), 192-203