Senior Solution Leader at Brane enterprises pvt ltd,India🎓
Dr. Pallavali Roja Rani, Ph.D. is a dedicated microbiologist with a robust focus on antimicrobial resistance, microbial biofilms, and biotechnological applications. Her work delves into understanding how microorganisms develop resistance to antibiotics, the role of biofilms in infections, and the use of CRISPR-Cas technology to explore resistance mechanisms. Additionally, Dr. Rani is passionate about environmental biotechnology, microbial symbiosis, and the human gut microbiome.
Professional Profile
🎓 Education
Dr. Rani earned her Ph.D. in Microbiology from Yogi Vemana University, India, in 2019. Her research focused on the isolation and characterization of bacteriophages against multi-drug resistant (MDR) bacteria, aiming to explore biological control mechanisms. She also holds a Master’s degree in Virology and a Bachelor’s degree in Biochemistry, Microbiology, and Chemistry, both from Sri Venkateswara University, Tirupathi.
🏢 Work Experience
Dr. Rani is currently a Senior Research Scientist at Brane Enterprises Pvt Ltd, Hyderabad, India, leading projects on the 3D representation of the human brain and microbial genomics within the Human Genome Project. Previously, she served as a Post-Doctoral Scientist at the Korean National University of Transportation and managed molecular diagnostics at the State COVID Hospital in India, where she oversaw over 15 million RT-PCR tests. She also has experience teaching microbiology at various universities and worked in molecular microbiology research labs.
🧬 Skills
Dr. Rani has extensive skills in molecular microbiology, including antimicrobial resistance mechanisms, bacteriophage therapy, biofilm disruption, microbial ecology, and gene cloning. She is proficient in advanced microbiological techniques such as RT-PCR, Next-Generation Sequencing (NGS), ELISA, and Western blotting. Additionally, she has hands-on experience with bioinformatics tools, statistical analysis (GraphPad Prism), and data visualization.
🏆 Awards and Honors
Throughout her career, Dr. Rani has been recognized for her outstanding contributions. She was awarded a Junior Research Fellowship from the Council of Scientific and Industrial Research (CSIR) and the prestigious Best Employee Award in 2021 for her leadership during the COVID-19 pandemic.
📚 Teaching Experience
With over a decade of teaching experience, Dr. Rani has mentored both undergraduate and graduate students in microbiology and biotechnology. She has also supervised large teams in laboratory settings, particularly during the pandemic, leading over 50 personnel in molecular diagnostics and research.
🔬 Research Focus
Her research centers on antibiotic resistance, microbial biofilms, phage therapy, and CRISPR-Cas applications in microbiology. She is particularly interested in microbial symbiosis, the role of microbiomes in health and disease, and the environmental applications of microbial communities in sustainable practices.
📚 Publications
- High throughput detection and genetic epidemiology of SARS-CoV-2 using COVIDSeq next-generation sequencing
RC Bhoyar, A Jain, P Sehgal, MK Divakar, D Sharma, M Imran, B Jolly, RR Pallavali, et al.
PloS One, 2021
- Isolation and in vitro evaluation of bacteriophages against MDR-bacterial isolates from septic wound infections
RR Pallavali, VL Degati, D Lomada, MC Reddy, VRP Durbaka
PloS One, 2017
- Green synthesis of silver nanoparticles and evaluation of their antibacterial activity against multidrug-resistant bacteria and wound healing efficacy using a murine model
V Lakkim, MC Reddy, RR Pallavali, KR Reddy, CV Reddy, Inamuddin, et al.
Antibiotics, 2020
- Symptomatic reinfection of SARS-CoV-2 with spike protein variant N440K associated with immune escape
PR Rani, M Imran, JV Lakshmi, B Jolly, A Jain, et al.
Journal of Medical Virology, 2021
- Data of antibacterial activity of plant leaves crude extract on bacterial isolates of wound infections
RR Pallavali, S Avula, VL Degati, M Penubala, AG Damu, VRP Durbaka
Data in Brief, 2019
- Lytic bacteriophages against bacterial biofilms formed by multidrug-resistant Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus
RR Pallavali, VL Degati, VR Narala, KK Velpula, S Yenugu, VRP Durbaka
Therapy, Applications, and Research, 2021
- Genetic epidemiology of variants associated with immune escape from global SARS-CoV-2 genomes
B Jolly, M Rophina, A Shamnath, M Imran, RC Bhoyar, MK Divakar, RR Pallavali, et al.
BioRxiv, 2020