Prof Dr. BASSEMSADEK | Neuropharmacology | Best Researcher Award

Prof Dr. BASSEMSADEK | Neuropharmacology | Best Researcher Award 🏆

Pharmacology and Therapeutics at College of Medicine and Health Sciences, United Arab Emirates University🎓

Dr. Bassem Shaban Sadek is a highly accomplished professor specializing in Pharmaceutical Medicinal Chemistry and Neuropharmacology. He is currently a Full Professor in the Department of Pharmacology and Therapeutics at the United Arab Emirates University, with ongoing research collaborations in Germany. His career spans over two decades of academic, research, and professional experience in both Europe and the Middle East.

Professional Profile 

Education

Dr. Sadek earned his Ph.D. in Pharmaceutical Medicinal Chemistry and Drug Design in 1999 from the Free University of Berlin (FUB), where his thesis focused on the development of selective and potent Histamine H3-Receptor Antagonists. He also holds a Bachelor of Pharmacy, which he received in 1994 from FUB.

 Work Experience

Throughout his career, Dr. Sadek has held various academic positions, starting as a Teaching Assistant at the Free University of Berlin, progressing to Assistant Professor roles at universities in the UAE and Germany. Notably, he was the Director of the Pharm-D Program at UAE University from 2015 to 2019. Since 2021, he has been a Full Professor at UAE University and a Research Associate at Heinrich Heine University in Düsseldorf, Germany.

 Skills 

Dr. Sadek has advanced expertise in preclinical research design and medical statistical analysis. He is proficient in statistical software like SPSS and GraphPad Prism, as well as molecular modeling tools such as ChemDraw, MOE, PyMol, and drug-likeness prediction programs. His knowledge extends to data analysis and visualization using Excel and PowerPoint.

Awards & Honors

Dr. Sadek has received numerous prestigious awards, including multiple Distinguished Research Awards for publishing in top international journals, Best Teacher Awards, and the ADEK Award for Research Excellence. His teaching and research have been recognized for excellence in both undergraduate and postgraduate education.

 Membership

He is actively involved in several professional bodies, including the Society for Neuroscience (SfN), the European Histamine Research Society (EHRS), and the German Pharmaceutical Association (DPhG). He also serves on editorial boards for various scientific journals and as a reviewer for major international funding bodies.

 

 Teaching Experience

Dr. Sadek has extensive teaching experience, offering courses in neuropharmacology, pharmacokinetics, and drug design for both undergraduate and postgraduate students. He has supervised numerous graduate theses and research projects, contributing to the academic development of his students.

 Research Focus

His research centers on preclinical drug development targeting neurodegenerative and behavioral disorders. He specializes in histamine H3 receptor antagonists, exploring their potential in treating conditions such as autism, epilepsy, and Alzheimer’s disease. Dr. Sadek employs cutting-edge in vivo and in vitro models to advance neuropharmacological research.

 

📖Publications : 

  • “Alleviation of Autophagic Deficits and Neuroinflammation by Histamine H3 Receptor Antagonist E159 Ameliorates Autism-Related Behaviors in BTBR Mice”
  • “The Microbiota–Gut–Brain Axis and Neurological Disorders: A Comprehensive Review”
  • “Targeting Microglia in Neuroinflammation: H3 Receptor Antagonists as a Novel Therapeutic Approach for Alzheimer’s Disease, Parkinson’s Disease, and Autism Spectrum Disorder”
  • “Apigenin Alleviates Autistic-like Stereotyped Repetitive Behaviors and Mitigates Brain Oxidative Stress in Mice”
  • “The Potent and Selective Histamine H3 Receptor Antagonist E169 Counteracts Cognitive Deficits and Mitigates Disturbances in the PI3K/AKT/GSK-3β Signaling Pathway in MK801-Induced Amnesia in Mice”
  • “Canagliflozin Ameliorates Oxidative Stress and Autistic-like Features in Valproic-Acid-Induced Autism in Rats: Comparison with Aripiprazole Action”
  • “Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin”
  • “Repurposing SGLT2 Inhibitors for Neurological Disorders: A Focus on the Autism Spectrum Disorder”
  • “Experimental Studies Indicate That ST-2223, the Antagonist of Histamine H3 and Dopamine D2/D3 Receptors, Restores Social Deficits and Neurotransmission Dysregulation in Mouse Model of Autism”
  • “Role of Brain Modulators in Neurodevelopment: Focus on Autism Spectrum Disorder and Associated Comorbidities”