Prof Dr. Hongjun JIN | Nuclear Medicine Molecular Imaging | Interdisciplinary Innovation Prize
: Sun Yat-sen University Fifth Affiliated Hospital, china
Profile
Education
Dr. Hongjun Jin is a Principal Investigator in Nuclear Medicine and a Doctoral Supervisor of Molecular Medicine at Sun Yat-sen University. He earned his PhD in Biochemistry from Texas A&M University in 2007, following a BS in Radiochemistry from Lanzhou University in 1994 and a BMed in Chinese Medicine from Beijing University of Chinese Medicine in 1997. He completed his postdoctoral training at PNNL from 2008 to 2012 and served as a radiology instructor at Washington University in St. Louis from 2012 to 2017. Since 2017, he has led the PET and radiochemical laboratory at his institute, having been recruited through Sun Yat-sen University’s “Hundred Talents Program.”
Research and Innovations:
1) General Research Fund for National Sciences Foundation of China (NSFC), 82372004,
“F-18 labelled PET probe targeting P2X7 receptor for Evaluation of Treatment for AD”
01/01/2024-12/31/2027¥480,000,
2) Key R&D project, 0007/2022/AKP, Macao S&T Fund (FDCT),“R&D of an Integrated
Molecular probe for Targeted TNFR2 New Tumor Diagnosis and
Treatment”,01/01/2024-12/31/2027,¥2,400,000 (out of ¥120,000,000)
3) Guangdong Provincial Enterprise Joint Fund, 2021A1515220004, Guangdong Province
“PET/MRI Neuromolecular Imaging Quantitative Study of New Drug Targeting Sigma1
Research Project
- 1) Outstanding Foreign Young Scientist Talent Program, RFIS, 82150610508 NSF-CN,
“ Establishment and drug evaluation of acetylcholinergic and dopaminergic
neuromolecular probes (18F VAT and 18F-DTBZ) PET brain imaging quantitative
system for Parkinson’s disease” 2022/01-2022/12,¥400,000 - General Research Fund for NSFC, 81871382, “F-18 labelled PET probe targeting P2X7
receptor for early detection of AD”01/01/2019-12/31/2022¥570,000 - SYSU “Hundred Talent “Starting Fund (Period I)” SYSU-FA10/01/2017-09/30/2022
¥2,500,000 - National Key R&D Program for Precision Medicine, 2018YFC0910601 Real-time, highdimensional, multi-modality imaging co-registration and theronoastic strategies for
oesophageal squamous-cell carcinomas10/01/2018-12/31/2020¥1,272,500 (out of
¥19,230,000) - Sun Yat-sen University Military Industry Cultivation Project, 89000-18843403 SYSU
“Key Technologies of Molecular Imaging of Immune Dysfunction in Microgravity
Environment”, 2019/08-2021/12¥1,890,00 - Researchers Initiate Clinical Research Project (IIT) Award, SYSU-FAH”A single-center,
open, prospective assessment of the diagnostic significance of 18F-FDG PET/CT
dynamic imaging and gene sequencing in detecting metastatic lesions of non-small cell
lung cancer”,2020/10-2021/09¥50,000 - COVID-19 infection prevention and control emergency S&T, ZH22036302200036PWC,
Zhuhai City”Specific Targeting S- protein of SARS-CoV-2 PET molecular imaging
probe”2020/08-2021/09,¥70,000
Citation Index:
h-index 26(total) 20 (since 2020)
i10-index 52(total) 39(since 2020)
Publications
- The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak–an update on the status
YR Guo, QD Cao, ZS Hong, YY Tan, SD Chen, HJ Jin, KS Tan, DY Wang, …Military medical research 7, 1-10
- Protein modifications as potential biomarkers in breast cancer
H Jin, RC ZangarBiomarker insights 4, BMI. S2557
- Generating circularly polarized luminescence from clusterization‐triggered emission using solid phase molecular self-assembly
P Liao, S Zang, T Wu, H Jin, W Wang, J Huang, BZ Tang, Y YanNature Communications 12 (1), 5496
- The human CC chemokine MIP-1β dimer is not competent to bind to the CCR5 receptor
H Jin, X Shen, BR Baggett, X Kong, PJ LiWangJournal of Biological Chemistry 282 (38), 27976-27983
- ZnAs@ SiO2 nanoparticles as a potential anti-tumor drug for targeting stemness and epithelial-mesenchymal transition in hepatocellular carcinoma via SHP-1/JAK2/STAT3 signaling
Y Huang, B Zhou, H Luo, J Mao, Y Huang, K Zhang, C Mei, Y Yan, H Jin, …Theranostics 9 (15), 4391
- The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak-an update on the status. Military Medical Research. 2020; 7 (1): 1-10
YR Guo, QD Cao, ZS Hong, YY Tan, SD Chen, HJ Jin, KS Tan, DY Wang, …doi. org/10.1186/s40779-020-00240-0
- Pharmacologic characterizations of a P2X7 receptor-specific radioligand,[11C] GSK1482160 for neuroinflammatory response
J Han, H Liu, C Liu, H Jin, JS Perlmutter, TM Egan, Z TuNuclear medicine communications 38 (5), 372-382
- Delivery of microRNA-10b with polylysine nanoparticles for inhibition of breast cancer cell wound healing
H Jin, Y Yu, WB Chrisler, Y Xiong, D Hu, C LeiBreast cancer: basic and clinical research 6, BCBCR. S8513
- Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein
X Zhang, H Jin, PK Padakanti, J Li, H Yang, J Fan, RH Mach, P Kotzbauer, …Applied Sciences 4 (1), 66-78
- Smoking, COPD, and 3-nitrotyrosine levels of plasma proteins
H Jin, BJ Webb-Robertson, ES Peterson, R Tan, DJ Bigelow, …Environmental Health Perspectives 119 (9), 1314-1320
- Binding of pyridine nucleotide coenzymes to the β-subunit of the voltage-sensitive K+ channel
SQ Liu, H Jin, A Zacarias, S Srivastava, A BhatnagarJournal of Biological Chemistry 276 (15), 11812-11820
- Synthesis and in vitro characterization of a P2X7 radioligand [123I] TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease
H Jin, J Han, D Resing, H Liu, X Yue, RL Miller, KM Schoch, TM Miller, …European journal of pharmacology 820, 8-17