Prof. Xinhong Zhu | Psychiatric Disorders | Best Researcher Award 

Prof. Xinhong Zhu’s academic journey is marked by exceptional accomplishments in medicine and neuroscience. He earned his M.D. from Henan Traditional Chinese Medical College, China, in 1991, laying a strong foundation in traditional Chinese medicine. He advanced his expertise with an M.S. in Chinese Integrative Medicine from The First Military Medical University in 2002, where he also completed his Ph.D. in Neuroscience in 2005. His global perspective was further enriched during his tenure as a visiting scientist at the IMMAG, Medical College of Georgia, USA, from January 2009 to August 2010, where he expanded his research capabilities in advanced neuroscience. This diverse and comprehensive education has equipped him to make pioneering contributions in medicine and neurobiology.

Work Experience 💼:

Prof. Xinhong Zhu has a distinguished career spanning clinical practice and academic leadership in neuroscience and integrative medicine. He is currently a Professor at South China University of Technology and Director of the Research Center for Brain Health at Pazhou Lab. Previously, he served as Executive Director of the Institute of Mental Health and Professor of Neurobiology at Southern Medical University. With roles ranging from clinician to educator and researcher, Prof. Zhu has significantly advanced neuroscience and brain health research.

Skills 🔍

Prof. Xinhong Zhu possesses exceptional skills in neuroscience research, particularly in studying neurobiological mechanisms and therapeutic strategies for mental health disorders. His expertise includes integrative medicine, with a strong foundation in traditional Chinese medical practices combined with modern biomedical approaches. He excels in advanced neurophysiology techniques, molecular biology, and pharmacological investigations. Additionally, Prof. Zhu has proven leadership and project management skills, directing multidisciplinary research centers and collaborative teams. His capabilities extend to teaching, mentoring, and publishing impactful scientific work, showcasing his ability to translate complex scientific concepts into practical applications.

Awards and Honors 🏆

Prof. Xinhong Zhu has received numerous prestigious awards and honors throughout his career, reflecting his significant contributions to neuroscience and integrative medicine. He was a recipient of the National Outstanding Youth Fund (2013) and was recognized among the Leading Talents in the Ten Thousand Talents Plan (2017). Prof. Zhu was honored as one of the Young and Middle-Aged Experts with Outstanding Contributions to National Health (2019). His groundbreaking research earned him the Second Prize in National Natural Science (2019) for work on new mechanisms and targets for antidepressants. He also secured the First Prize of Guangdong Provincial Science and Technology Progress Award twice, for his research on neuroprotective targets for ischemic stroke (2010) and novel antidepressant targets and methods (2016). These accolades underscore his influential role in advancing brain health and therapeutic innovations.

Research Interests:

Prof. Xinhong Zhu’s research interests lie at the intersection of neuroscience, integrative medicine, and brain health. He focuses on uncovering new mechanisms and therapeutic targets for neuropsychiatric disorders, including depression, anxiety, and autism. His work also explores neuroprotective strategies for ischemic stroke and innovative methods for antidepressant development. Prof. Zhu’s interdisciplinary approach bridges traditional Chinese medicine and modern neuroscience, aiming to enhance psychological resilience and neurobiological understanding through cutting-edge research.

📚 Publications 

• Title: Discovery of Glycosidated Glycyrrhetinic Acid Derivatives: Natural Product-Based Soluble Epoxide Hydrolase Inhibitors
  • Authors: Q. Liu, Y.-X. Wang, Z.-H. Ge, X.-H. Zhu, J.-H. Liang
  • Journal: European Journal of Medicinal Chemistry
  • Year: 2024
  • Volume/Issue: 280, 116937
  • Citations: 0
• Title: Discovery of Orally Active Phenylquinoline-Based Soluble Epoxide Hydrolase Inhibitors with Anti-Inflammatory and Analgesic Activity
  • Authors: J. Ding, M.-Z. Zhu, S.-M. Liu, X.-H. Zhu, J.-H. Liang
  • Journal: Journal of Medicinal Chemistry
  • Year: 2024
  • Volume/Issue: 67(20), 18412–18447
  • Citations: 0
• Title: Discovery of a Novel Lead Characterized by a Stilbene-Extended Scaffold Against Sepsis as Soluble Epoxide Hydrolase Inhibitors
  • Authors: Z.-Q. Feng, J. Ding, M.-Z. Zhu, X.-H. Zhu, J.-H. Liang
  • Journal: European Journal of Medicinal Chemistry
  • Year: 2024
  • Volume/Issue: 266, 116113
  • Citations: 3
• Title: Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice
  • Authors: Y.-D. Pan, Y. Zhang, W.-Y. Zheng, Q.-Q. Wen, X.-H. Zhu
  • Journal: Journal of Neuroscience
  • Year: 2024
  • Volume/Issue: 44(7), e1665232023
  • Citations: 0
• Title: Enhancing HIF-1α–P2X2 Signaling in Dorsal Raphe Serotonergic Neurons Promotes Psychological Resilience
  • Authors: Y. Zhang, Y.-D. Pan, W.-Y. Zheng, N. Mechawar, X.-H. Zhu
  • Journal: Redox Biology
  • Year: 2024
  • Volume/Issue: 69, 103005
  • Citations: 1
• Title: Hepatic Soluble Epoxide Hydrolase Activity Regulates Cerebral Aβ Metabolism and the Pathogenesis of Alzheimer’s Disease in Mice
  • Authors: Y. Wu, J.-H. Dong, Y.-F. Dai, Y.-Q. Li, X.-H. Zhu
  • Journal: Neuron
  • Year: 2023
  • Volume/Issue: 111(18), 2847–2862.e10
  • Citations: 21
• Title: Deletion of Transferrin Receptor 1 in Parvalbumin Interneurons Induces a Hereditary Spastic Paraplegia-Like Phenotype
  • Authors: W. Xiong, L. Jin, Y. Zhao, Y. Pan, X. Zhu
  • Journal: Journal of Neuroscience
  • Year: 2023
  • Volume/Issue: 43(27), 5092–5113
  • Citations: 0
• Title: A Thalamic-Primary Auditory Cortex Circuit Mediates Resilience to Stress
  • Authors: H.-Y. Li, M.-Z. Zhu, X.-R. Yuan, Y.-Q. Li, X.-H. Zhu
  • Journal: Cell
  • Year: 2023
  • Volume/Issue: 186(7), 1352–1368.e18
  • Citations: 19

Conclusion