Muhammad Afzal | Pharmacology | Excellence in Research

Prof. Muhammad Afzal | Pharmacology | Excellence in Research   🏆

Professor at Batterjee Medical College, Saudi Arabia

Prof. Muhammad Afzal is a distinguished academic and researcher specializing in drug discovery and development, anticancer drug discoveries, neuropharmacology, and endocrinology. He holds a Ph.D. in Pharmacology from Pacific Academy of Higher Education and Research University, Udaipur, and has extensive experience in pharmacology and pharmaceutical sciences. Currently, he serves as a Professor and Research Coordinator at Batterjee Medical College, Jeddah, Saudi Arabia. Prof. Afzal has contributed significantly to scientific research, with expertise in various animal models and advanced analytical techniques. His work has earned him notable recognition, including a Research Excellence Award from Jouf University, Saudi Arabia, and selection for Post-Doctoral Research at the Institute of Post Graduate Studies, Malaysia. Prof. Afzal’s innovative research, particularly in the fields of neuropharmacology and endocrine disorders, continues to have a profound impact on both academics and the broader scientific community.

Profile

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Education 🎓:

Prof. Muhammad Afzal completed his Ph.D. in Pharmacology from Pacific Academy of Higher Education and Research University, Udaipur, in 2014. Prior to that, he earned his M. Pharm in Pharmacology from S.K. Patel College of Pharmaceutical Education & Research, Ganpat University, Mehsana, in 2009. He also holds a B. Pharm degree from HNB Garhwal University, Shrinagar, Uttarakhand, awarded in 2007. Additionally, Prof. Afzal is a registered pharmacist with the Uttar Pradesh Pharmacy Council (Reg. No. 50848). His academic journey reflects a solid foundation in pharmacology, supported by his successful completion of the IELTS (International English Language Testing System) with an overall score of 6 bands, which he undertook at the IDP Centre, Aljouf University, Sakaka, Saudi Arabia, in December 2021. This diverse educational background highlights Prof. Afzal’s comprehensive expertise in pharmaceutical sciences and his commitment to continuous learning and professional development.

Work Experience 💼:

Prof. Muhammad Afzal has extensive academic and research experience in the field of pharmacology and pharmaceutical sciences. He currently serves as a Professor and Research Coordinator at the Department of Pharmaceutical Sciences, Batterjee Medical College, Jeddah, Saudi Arabia, where he contributes to both teaching and research activities. Prior to this, he worked as a Professor at the Department of Pharmacology, Himalayan Institute of Pharmacy and Research, Dehradun, where he delivered lectures on Physiology, Pathophysiology, Anatomy, and Pharmacology to postgraduate and undergraduate pharmacy students. Prof. Afzal’s professional journey also includes significant research involvement, where he has led numerous studies on drug discovery, anticancer drug development, and neuropharmacology. His research expertise extends to animal models, analytical techniques, and the establishment of the mechanism of action of drugs, making him a valuable contributor to advancing the field of pharmacological research.

Skills 🔍

Prof. Muhammad Afzal possesses a diverse set of research and technical skills that span across various domains of pharmacology and drug discovery. He is highly proficient in the use of advanced analytical instruments, such as UV spectrophotometers, semi-auto analyzers, fully automated hematology analyzers, RT-PCR, ELISA readers, and western blot analyzers. His expertise extends to the mechanism of drug action, where he has successfully established drug interactions using various experimental animal models. Prof. Afzal is also skilled in animal handling, working with species such as rats, mice, guinea pigs, and rabbits, and is well-versed in administering drugs through different routes. Furthermore, his technical competence includes the use of Langendorff’s assembly for cardiac studies and various biological assays for testing drug efficacy, such as those related to asthma, diabetes, inflammatory bowel disease, cancer, and cardiovascular diseases. His ability to utilize state-of-the-art research techniques and conduct preclinical studies has made him a valuable asset in the pharmaceutical research community.

Research Interests:

Prof. Muhammad Afzal’s primary research interests lie in the fields of drug discovery and development, with a particular focus on anticancer drug discoveries, neuropharmacology, and endocrinology. He is dedicated to exploring innovative approaches in pharmacology, particularly in the development of novel therapies for cancer, neurological disorders, and endocrine-related diseases. Prof. Afzal is also deeply involved in studying the mechanisms of drug action using various animal models for diseases like diabetes, hypertension, asthma, anti-inflammatory disorders, and cardiovascular diseases. His work integrates both in vivo and computational techniques to investigate the biochemical, histopathological, and molecular interactions of therapeutic agents. Additionally, Prof. Afzal’s research focuses on understanding the pathophysiological processes underlying neurodegenerative diseases such as Huntington’s disease and diabetes, with the aim of developing targeted treatments for these complex conditions.

📚 Publications 

  • Title: Ectopic Pregnancy: A Review
    • Authors: P Rana, I Kazmi, R Singh, M Afzal, FA Al-Abbasi, A Aseeri, R Singh et al.
    • Journal: Archives of Gynecology and Obstetrics
    • Year: 2013
    • Citations: 233
  • Title: Sedative, Antiepileptic, and Antipsychotic Effects of Viscum album L. (Loranthaceae) in Mice and Rats
    • Authors: G Gupta, I Kazmi, M Afzal, M Rahman, S Saleem, MS Ashraf, MJ Khusroo et al.
    • Journal: Journal of Ethnopharmacology
    • Year: 2012
    • Citations: 176
  • Title: Classical to Current Approach for Treatment of Psoriasis: A Review
    • Authors: M Rahman, K Alam, M Zaki Ahmad, G Gupta, M Afzal, S Akhter, I Kazmi et al.
    • Journal: Endocrine, Metabolic & Immune Disorders-Drug Targets
    • Year: 2012
    • Citations: 158
  • Title: Anti-inflammatory and Analgesic Potential of a Novel Steroidal Derivative from Bryophyllum pinnatum
    • Authors: M Afzal, G Gupta, I Kazmi, M Rahman, O Afzal, J Alam, KR Hakeem et al.
    • Journal: Fitoterapia
    • Year: 2012
    • Citations: 127
  • Title: Advancement in Multifunctional Nanoparticles for the Effective Treatment of Cancer
    • Authors: M Rahman, MZ Ahmad, I Kazmi, S Akhter, M Afzal, G Gupta et al.
    • Journal: Expert Opinion on Drug Delivery
    • Year: 2012
    • Citations: 127

Conclusion 

Prof. Muhammad Afzal’s outstanding research in drug discovery, neuropharmacology, and endocrinology, his leadership in academic settings, and his international recognition make him an exemplary candidate for the Research for Excellence in Research award. His ability to conduct groundbreaking research while mentoring future scientists positions him as a true leader in his field.

Joanna Jazowiecka-Rakus | oncolytic virotherapy | Best Researcher Award

Joanna Jazowiecka-Rakus | oncolytic virotherapy | Best Researcher Award🏆


Assistant Professor at Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland
🎓

Joanna Jazowiecka-Rakus is an Assistant Professor with a strong focus on advancing cancer research through innovative oncolytic therapies. Her work at the Maria Skłodowska Memorial National Institute of Oncology in Gliwice, Poland, positions her as a leading expert in experimental cancer treatments. Dr. Jazowiecka-Rakus’s pioneering research in oncolytic virotherapy and nanocarrier drug delivery aims to address complex cancers like pancreatic adenocarcinoma, glioma, and melanoma. With a reputation for pushing boundaries in cancer treatment, she continues to make strides in developing therapies that offer new hope for patients with challenging diagnoses.

Professional Profile 

🎓 Education

Dr. Jazowiecka-Rakus holds a Master of Science in Biology from the Faculty of Biology, University of Silesia, Katowice, Poland (2001), followed by a Ph.D. in Medical Biology from the National Institute of Oncology, Warsaw, Poland (2007). In recognition of her exceptional contributions to cancer research, she earned a D.Sc. (habilitation) in Medical Sciences from the same institution. Her academic path reflects her dedication to enhancing cancer treatment through rigorous scientific training and specialization.

🏢 Work Experience

Throughout her career, Dr. Jazowiecka-Rakus has held esteemed research positions, including her current role as an Assistant Professor at the National Institute of Oncology. Her work has been instrumental in projects funded by prestigious institutions like the International Center for Genetic Engineering and Biotechnology and the National Science Center of Poland. Notably, her research covers a wide spectrum of experimental cancer therapies, including the use of myxoma viruses and mesenchymal stem cells to treat melanoma, ovarian cancer, and glioma. She has also forged valuable collaborations with global institutions, such as the Biodesign Institute at the University of Arizona, Tempe, USA.

🧬 Skills

Dr. Jazowiecka-Rakus brings a wealth of expertise in cancer treatment, highlighted by her skills in oncolytic virotherapy, cancer immunotherapy, and advanced drug delivery systems. Her work with oncolytic virotherapy focuses on developing viral therapies that specifically target and destroy cancer cells, offering a promising alternative to traditional cancer treatments. In cancer immunotherapy, she integrates immune-enhancing agents to create therapies for advanced cancers. Her pioneering methods for stem cell-based drug delivery use mesenchymal stem cells as carriers for oncolytic viruses, targeting tumor cells more effectively. Additionally, she has developed nanocarrier drug formulations that improve the delivery and efficacy of drugs in cancer treatment.

Awards and Honors 🏆

Dr. Jazowiecka-Rakus’s dedication to cancer research has earned her numerous accolades. Between 2017 and 2020, she was awarded a research grant by the International Center for Genetic Engineering and Biotechnology to study oncolytic melanoma therapy, underlining her impact in this vital area. Her scholarly contributions include 18 articles published in high-impact journals indexed in Web of Science and Scopus, reflecting her influence and recognition within the cancer research community. Her works have accumulated a citation index of over 431, showcasing the significant reach and impact of her research.

🌐 Memberships

Active in professional societies, Dr. Jazowiecka-Rakus is an auditor for the Association for the Support of Cancer Research in Gliwice, Poland, where she contributes to promoting research integrity and supporting advancements in cancer studies. She is also a member of the Polish Radiation Research Society based in Warsaw, where she engages with other professionals dedicated to improving cancer treatment and sharing knowledge within the field.

📚 Teaching Experience

As an Assistant Professor, Dr. Jazowiecka-Rakus is committed to educating and mentoring the next generation of cancer researchers at the National Institute of Oncology. Her teaching covers essential aspects of oncology and medical biology, with a particular focus on innovative treatment strategies in cancer research. Through her courses and mentoring, she guides students in understanding the complexities of cancer treatment, encouraging them to pursue research that makes a real-world impact.

🔬 Research Focus

Dr. Jazowiecka-Rakus’s research centers on developing experimental therapies for aggressive cancers. Her work includes the creation of oncolytic myxoma virus constructs, which use mesenchymal stem cells as carriers to deliver viral therapies specifically targeting cancers such as pancreatic adenocarcinoma and glioma. She has developed advanced blood-brain barrier crossing techniques to treat glioma through intra-arterial delivery, offering a new method to target brain tumors effectively. Additionally, her research on 3D models for cancer uses spheroid and organoid models to test therapies for disseminated ovarian cancer, pushing the boundaries of cancer treatment with innovative laboratory models that mimic real-world conditions. Dr. Jazowiecka-Rakus’s interdisciplinary approach highlights her dedication to advancing the field of cancer therapy and improving patient outcomes.

Conclusion 

In conclusion, Dr. Joanna Jazowiecka-Rakus exemplifies the qualities of an outstanding researcher through her innovative projects, significant contributions to cancer research, and a strong academic foundation. Her ongoing work and potential for future advancements make her a deserving candidate for the Best Researcher Award. Enhancing her publication record and pursuing patent opportunities would further solidify her standing as a leader in the field.

📚 Publilcation 

  • Adipose-Derived Stem Cells as Carrier of Pro-Apoptotic Oncolytic Myxoma Virus: To Cross the Blood–Brain Barrier and Treat Murine Glioma
  • Combination of LIGHT (TNFSF14)-Armed Myxoma Virus Pre-Loaded into ADSCs and Gemcitabine in the Treatment of Experimental Orthotopic Murine Pancreatic Adenocarcinoma
  • Myxoma Virus Expressing LIGHT (TNFSF14) Pre-Loaded into Adipose-Derived Mesenchymal Stem Cells Is Effective Treatment for Murine Pancreatic Adenocarcinoma
  • Removal of Heavy Metal Ions from Wastewaters: An Application of Sodium Trithiocarbonate and Wastewater Toxicity Assessment
  • COVID-19 Autopsies: A Case Series from Poland
  • Myxoma Virus-Loaded Mesenchymal Stem Cells in Experimental Oncolytic Therapy of Murine Pulmonary Melanoma
  • Mesenchymal stem cells as carriers for systemic delivery of oncolytic viruses