Agota Apati | Stem Cell Based Disease Modelling | Best Researcher Award

Dr. Agota Apati | Stem Cell Based Disease Modelling | Best Researcher Award

Dr. Ágota Apáti, PhD, DSc, is a distinguished Hungarian molecular biologist and Senior Research Associate at the Institute of Molecular Life Sciences, Research Centre for Natural Sciences. She leads the Pluripotent Stem Cell Laboratory and is renowned for establishing Hungary’s first human pluripotent stem cell lab. With over 70 publications and an H-index of 25, her work is widely recognized internationally. Dr. Apáti’s research encompasses human iPSC-derived disease models, membrane transporters, and cellular signaling pathways, with implications in schizophrenia, diabetes, and rare syndromes. She has supervised numerous PhD students and maintains active roles in both national and international scientific societies. Her commitment to translational stem cell research and ethical scientific practice positions her as a leading figure in the field of regenerative medicine and cellular therapeutics.

Profile

🎓 Education

Dr. Ágota Apáti holds a Master of Science (MSc) degree in Chemistry from Eötvös Loránd University of Sciences, Budapest (1984–1989). She later pursued doctoral studies and earned her PhD from Semmelweis Medical University (1998–2003), focusing on molecular and cellular aspects of hematology and immunology. Her academic training blends rigorous biochemical education with advanced medical sciences, establishing a solid foundation for her research career in stem cell biology and cellular therapeutics. Through continuous engagement in teaching and supervising graduate students, she has also remained an integral part of academic development at Hungary’s premier institutions. Her strong interdisciplinary background supports her work on complex cellular processes and disease modeling, and she is also a Doctor of Science (DSc, 2024) from the Hungarian Academy of Sciences—an honor awarded for substantial contributions to biomedical research in Hungary.

🧪 Experience

With over three decades of research experience, Dr. Ágota Apáti began her scientific career as a Research Fellow at Semmelweis Medical University (1989–1993). She progressed through multiple institutions, including the National Institute of Haematology and Immunology (1993–2004) and the National Blood Service (2005–2013), where she led various molecular biology projects. Between 2013 and 2023, she was a Senior Research Associate and lab head at the Institute of Enzymology, Hungarian Academy of Sciences. Since 2023, she continues her leadership as Laboratory Head at the Institute of Molecular Life Sciences under HUNREN. She has consistently taught and mentored postgraduate students in biochemistry, hematology, immunology, and membrane biology. Dr. Apáti’s collaborative and interdisciplinary projects have helped develop multiple disease models and cellular assays. Her scientific leadership has been instrumental in expanding Hungary’s role in cutting-edge stem cell research and molecular diagnostics.

🏅 Awards and Honors

Dr. Ágota Apáti has been recognized both nationally and internationally for her contributions to biomedical research. Early in her career, she received the prestigious UNIDO award during the ICRO course on RNA structure and function in Trieste, Italy (1994). In 2024, she was awarded the Doctor of Science (DSc) degree by the Hungarian Academy of Sciences—a distinguished title granted to researchers with a substantial, impactful body of scientific work. Her membership in renowned scientific organizations, such as the International Society for Stem Cell Research (ISSCR), Hungarian Society of Biology, Hungarian Society of Biochemistry, and the Hungarian Medical Research Council’s Ethical Board for Human Reproduction, underscores her stature in the field. These accolades not only reflect her scientific excellence but also her contributions to ethical research practice, public health, and mentoring within the scientific community, cementing her reputation as a key contributor to molecular life sciences.

🔬 Research Focus

Dr. Apáti’s research centers on pluripotent stem cells, disease modeling, and cellular signaling. She specializes in generating and differentiating human induced pluripotent stem cells (iPSCs) into neuronal, cardiac, mesenchymal, and endothelial lineages. Her work extends into disease modeling for schizophrenia, arteriosclerosis, diabetes, DiGeorge syndrome, and Frank-Ter Haar syndrome using patient-derived iPSC lines and CRISPR-based genome editing. She has developed cellular reporter systems to study membrane transporter function and calcium signaling pathways, significantly advancing understanding in neuropsychiatric and cardiovascular disorders. Through integrative omics and 3D organoid models, Dr. Apáti’s lab explores metabolic and genetic dysregulation in human pathologies. Her translational research aims to identify drug targets and therapeutic strategies using patient-specific cell lines. She also investigates multidrug resistance in stem cells and cancer, contributing to better clinical interventions. Her multidisciplinary projects bridge fundamental biology with clinical relevance, making her a vital contributor to regenerative medicine and personalized therapy.

Conclusion

Dr. Ágota Apáti is a trailblazing scientist whose pioneering work in human stem cell research, disease modeling, and membrane biology continues to shape translational medicine, with a sustained commitment to research excellence, scientific mentorship, and ethical innovation in biomedical sciences.

Publications

  • Haloperidol, Olanzapine, and Risperidone Induce Morphological Changes in an In Vitro Model of Human Hippocampal Neurogenesis

    Biomolecules
    2024-06 | Journal article | Author
    CONTRIBUTORS: Bálint Jezsó; Sára Kálmán; Kiara Gitta Farkas; Edit Hathy; Katalin Vincze; Dzsenifer Kovács-Schoblocher; Julianna Lilienberg; Csongor Tordai; Zsofia Nemoda; László Homolya et al.
  • Partial Disturbance of Microprocessor Function in Human Stem Cells Carrying a Heterozygous Mutation in the DGCR8 Gene

    Genes
    2022-10 | Journal article | Author
    CONTRIBUTORS: Dóra Reé; Ábel Fóthi; Nóra Varga; Orsolya Kolacsek; Tamas Orban; Agota Apat
  • A Novel Cell-Based Model for a Rare Disease: The Tks4-KO Human Embryonic Stem Cell Line as a Frank-Ter Haar Syndrome Model System

    International Journal of Molecular Sciences
    2022-08 | Journal article | Author
    CONTRIBUTORS: Loretta László; Hédi Maczelka; Tamás Takács; Anita Kurilla; Álmos Tilajka; László Buday; Vas Virag; Agota Apati
  • Synthesis and Systematic Investigation of Lepidiline A and Its Gold(I), Silver(I), and Copper(I) Complexes Using In Vitro Cancer Models and Multipotent Stem Cells

 

Jim Jinn-Chyuan Sheu | Precision medicine | Best Researcher Award

Dr. Jim Jinn-Chyuan Sheu | Precision medicine | Best Researcher Award

Dr. Jim Jinn-Chyuan Sheu is a professor at the Institute of Biomedical Sciences, National Sun Yat-sen University, Taiwan, and an adjunct professor in several prestigious institutions. With a PhD in Life Science from National Tsing-Hua University, his academic and industrial experiences span cancer genetics, precision medicine, and biopharmaceuticals. He has held positions at Johns Hopkins Medical Institutions and Development Center for Biotechnology. His research explores molecular mechanisms underlying diseases such as cancer and endometriosis, employing genome-wide technologies to identify biomarkers and drug targets. He actively contributes to biomedical innovation, translational medicine, and mentorship. Dr. Sheu has received numerous national and international awards, including the Wu-Da-You Memorial Award and Sigma Xi membership. He is also an ambassador for the European Association for Cancer Research. As a prolific researcher and reviewer, he plays key roles in research councils and institutional review boards, helping shape scientific policy and translational biomedical advancements in Taiwan and beyond.

Profile

Education 🎓

Dr. Sheu earned his Ph.D. in Life Science from National Tsing-Hua University, Taiwan, in 2002, where he focused on advanced molecular biology, gene expression regulation, and biomedical research. His doctoral training provided a strong foundation in cancer genetics and systems biology. Earlier, he completed his B.S. in Biology (now Life Science) from Fu-Jen University in 1994, building core competencies in biological sciences and cellular mechanisms. These educational milestones equipped him with theoretical knowledge and technical skills in genomics, proteomics, and cellular signaling, which are now reflected in his research on chromatin remodeling, cancer biomarkers, and therapeutic targets. Through rigorous academic mentorship, Dr. Sheu gained early exposure to multidisciplinary research and critical analysis, fostering his interest in precision medicine. His academic background laid the groundwork for his contributions to biomedical research, drug development, and translational science. These formative years in Taiwan’s top universities underpin his long-standing excellence in scientific discovery and innovation.

Experience 👨‍🏫

Dr. Sheu’s professional experience includes faculty roles and research leadership across academia and industry. He has served as a Professor at National Sun Yat-sen University since 2014 and previously held faculty roles at China Medical University. Internationally, he was a Research Fellow at Johns Hopkins Medical Institutions (2004–2006). Between 2003–2004, he worked in various leadership positions at the Development Center for Biotechnology, including Director of Protein Drugs Division and Project Leader. His postdoctoral and early research roles included work with Dr. Tse-Wen Chang and Dr. Carmay Lim at Academia Sinica. His academic leadership includes roles such as Associate VP of R&D, Chair of the Institute of Biomedical Sciences, and Director of Research Resources at NSYSU. He has reviewed research proposals for numerous hospitals and institutions, served on IRBs, and guided government research policy. His diverse experience bridges basic science, translational research, and biomedical entrepreneurship with national and global impact.

Awards & Recognitions 🏅

Dr. Sheu has received over 30 prestigious awards. In 2023 alone, he earned the Tien-Te Lee Award, NSYSU Outstanding Faculty Award, and top honors at the 37th Joint Biomedical Conference. He previously received the Prof. Chii-Ruey Tzeng Award, Sigma Xi membership (2021), and EACR Ambassador role (2020). His innovation was recognized by Future Tech Award and the 2020 Smart Life Innovation Competition. His studies were featured as Taiwan Research Highlights and F1000Prime recommendations. He was the 2014 recipient of the Wu-Da-You Memorial Award and the IBC Outstanding Scientific Achievement Award. He received the Medical Young Investigator Award in 2009 and the Best Basic Science Award at Johns Hopkins in 2005. As a government-financed scholar to the U.S., his academic excellence has been internationally recognized. He consistently ranks among Taiwan’s top biomedical researchers, illustrating his impact through award-winning research in endometriosis, cancer stemness, diagnostics, and therapeutic innovation.

Research Interests 🔬

Dr. Sheu’s research focuses on cancer genetics and genomics, endometriosis, precision medicine, chromatin remodeling, cytoskeletal dynamics, cell adhesion and invasion, and mechanotransduction. His lab investigates how abnormalities in gene expression and chromatin structure drive disease progression, especially in gynecologic cancers and endometriosis. By applying genome-wide analysis and bioinformatics, his team identifies disease-driving genes and develops novel diagnostic tools and therapeutic strategies. A key interest is the tumor microenvironment and how cytoskeletal networks and nuclear architecture influence cancer stemness and metastasis. His group explores traditional Chinese medicine compounds and stem cell therapies, advancing integrative approaches to medicine. Antibody and vaccine engineering are also integral to his translational pipeline. Funded by NSTC Taiwan and other institutions, his projects target non-invasive diagnostics and biomarker-based interventions. His long-term vision involves bridging molecular biology, clinical application, and therapeutic innovation to impact patient care and global health through interdisciplinary and precision-driven biomedical science.

Publications

PhongSon Dinh | Gene function analysis | Best Researcher Award

Dr. PhongSon Dinh | Gene function analysis | Best Researcher Award

Dr. Dinh Phong Son is a prominent researcher at Duy Tan University, Vietnam, specializing in laboratory medicine and molecular medicine. With a PhD from Guangxi Medical University, China, he is dedicated to advancing the field of molecular biology and medical diagnostics. His work focuses on identifying biomarkers for early disease detection and investigating gene targets for targeted therapies. He actively contributes to scientific advancements in understanding complex diseases such as cancer, diabetes, and cardiovascular diseases. Through his expertise in molecular techniques like CRISPR/Cas9, PCR, and sequencing, Dr. Son plays a vital role in improving medical diagnostics and treatments. 🧬🔬

Profile

Education 🎓

Dr. Dinh Phong Son holds a Doctorate (Ph.D.) in Molecular Medicine from Guangxi Medical University, China, after earning his degree in Laboratory Medicine from Hue University of Medicine and Pharmacy, Vietnam. His educational background has equipped him with the expertise in molecular biology, enabling him to explore complex diseases at a molecular level and work on cutting-edge technologies in the field of gene editing and disease diagnosis. 🎓📚

Experience 👨‍🏫

Dr. Dinh Phong Son has significant experience in molecular medicine, focusing on the development of biomarkers for early disease diagnosis and treatment. With expertise in molecular biology techniques such as PCR, qPCR, CRISPR/Cas9, and sequencing, he has conducted extensive research on diseases like cancer, cardiovascular disorders, and diabetes. His work integrates bioinformatics and molecular assays to understand gene functions and identify potential drug targets. He is actively contributing to scientific publications and advancing the research community’s knowledge in disease diagnostics and therapies. 🔬💡

Research Interests 🔬

Dr. Dinh Phong Son’s research focuses on molecular techniques for disease detection and gene therapy. His current work includes exploring circRNA, miRNA, mRNA, and their role in diseases like coronary heart disease and cancer. Dr. Son is particularly interested in developing diagnostic biomarkers and therapeutic targets for systemic diseases using next-generation sequencing and CRISPR/Cas9. He also investigates the interaction networks between lncRNA, circRNA, miRNA, genes, and proteins, aiming to create molecular-based solutions for precision medicine. His research paves the way for future advancements in molecular diagnostics and personalized therapies. 🔬🧬

Awards & Recognitions 🏅

Dr. Dinh Phong Son’s contributions to molecular medicine have earned him recognition in the scientific community. His research publications, particularly on gene networks and biomarkers in cardiovascular and cancer research, have garnered widespread attention. He is currently a nominee for the Best Researcher Award, reflecting his ongoing commitment to advancing the fields of molecular biology, gene therapy, and disease diagnostics. His work is an important step toward improving public health outcomes through the application of molecular techniques. 🏆🏅

Publications 📚

  • Identification and assessment of hub genes and miRNAs coregulatory associated with immune infiltrations and drug interactions in latent tuberculosis based on MicroarrayData analysis, molecular docking, and dynamic simulation

    Biochemistry and Biophysics Reports
    2025-03 | Journal article
    CONTRIBUTORS: PhongSon Dinh; ChauMyThanh Tran; ThiPhuongHoai Dinh; Hai-Anh Ha; Aigul Utegenova; Awais Ali; Abdulaziz Alamri
  • Hsa_circRNA_0000284 acts as a ceRNA to participate in coronary heart disease progression by sponging miRNA-338-3p via regulating the expression of ETS1

    Journal of Biomolecular Structure and Dynamics
    2024-07-02 | Journal article
    CONTRIBUTORS: PhongSon Dinh; ChauMyThanh Tran; ThiPhuongHoai Dinh; Awais Ali; ShangLing Pan
  • Potential diagnostic value of serum microRNAs for 19 cancer types: a meta-analysis of bioinformatics data

    Journal of Biomolecular Structure and Dynamics
    2024-03-15 | Journal article
    CONTRIBUTORS: ChauMyThanh Tran; PhongSon Dinh
  • Identification of hsa_circ_0001445 of a novel circRNA-miRNA-mRNA regulatory network as potential biomarker for coronary heart disease

    Frontiers in Cardiovascular Medicine
    2023-03-14 | Journal article
    Part of ISSN: 2297-055X
    CONTRIBUTORS: PhongSon Dinh; JunHua Peng; ThanhLoan Tran; DongFeng Wu; ChauMyThanh Tran; ThiPhuongHoai Dinh; ShangLing Pan

Shilpa Kumari | Biotechnology | Best Researcher Award

Ms.Shilpa Kumari | Biotechnology | Best Researcher Award

 

Sharda University, India

Profile

Education

She is currently pursuing a Ph.D. at Sharda University since 2020, having completed her coursework with an impressive 84.5%. She holds an M.Sc. in Biotechnology from Chandigarh University, where she secured 79.6% in 2019. Prior to that, she earned her B.Sc. from HNB Garhwal Central University, Srinagar, in 2017 with a score of 66.7%. She completed her 12th grade in the Medical stream under CBSE in 2014 with 74.4% and her 10th grade in General Science in 2012, securing 75.5%.

 

Awards

She has been awarded the Sharda University Research Scholarship (SURS) by Sharda University since February 2021. She received a Silver Medal at the 8th Annual Meeting of the International Association of Zoologists and the 5th International Conference on Recent Trends in Life Sciences and Biotechnology held at Maharishi Markandeshwar (Deemed to be University), Haryana, in December 2024. Additionally, she was granted International Travel Support from the Science and Engineering Research Board (SERB), Department of Science and Technology, Government of India, to present her research at the University Malay, Kuala Terengganu, Malaysia, in August 2024. She secured 2nd Prize at the Anveshan International Convention 2023-2024 (North Zone), organized by the Association of Indian Universities (AIU) in January 2024. Furthermore, she won the Best Oral Presentation Award at the National Conference on Disease Diagnosis and Drug Development Against Human Pathogens, sponsored by DBT and organized by Muthyammal College of Arts and Science in November 2023.

Book chapters

1. Shilpa Kumari, Neha Verma, Anil Kumar, Sunita Dalal, and Kanu Priya. “Functional
overrepresentation analysis and their application in microbial pathogenesis.” In Systems Biology
Approaches for Host-Pathogen Interaction Analysis, pp. 171-179. Academic Press, 2024.
2. Neha Verma, Shilpa Kumari, Anil Kumar, and Kanu Priya. “Advancements in systems biologybased analysis of microbial pathogenesis.” In Systems Biology Approaches for Host-Pathogen
Interaction Analysis, pp. 181-190. Academic Press, 2024

Publication

NORMA SILVA | Biotechnology | Women Researcher Award

Dr.Norma Silva | Biotechnology | Women Researcher Award

 

The university of Arizona, United States

Profile

Education

She holds a Biotechnology Engineering degree from the Technological Institute of Sonora (1991-1996) and a Master’s in Environmental Sciences and Sustainable Development from the Autonomous University of Sinaloa (2001-2004). She later earned a Ph.D. in Sciences with a Specialization in Biotechnology through the National Program (PNPC) of Biological Sciences of the Northwest, CONACYT, at the Technological Institute of Sonora (2010-2014). Additionally, she has obtained diplomas in teaching, generic competencies, and nutrition

Work experience

She worked as a Laboratory Technician at SABRITAS, S.A. de C.V. (1994-1998), where she was responsible for quality control of physicochemical parameters in raw materials, processes, and packaging lines. From 2001 to 2004, she served as a Professor at Colegio Sinaloa in Culiacán, teaching chemistry, biology, and food analysis. She then worked as an Adjunct Professor in the Department of Architecture and Environmental Engineering at the Technological Institute of Cajeme (ITESCA) from 2006 to 2008. Additionally, she held a dual role as a Professor and Academic Administrator in the Department of Biotechnology and Food Sciences at the Technological Institute of Sonora (ITSON) between 2001 and 2014. In 2011, she was an Adjunct Professor at Tecnológico de Monterrey, teaching Organic Chemistry in English. She later joined the University of Sonora (UNISON) as an Adjunct Professor from 2013 to 2016 and again in 2024. From 2017 to 2022, she worked as a Determined Research Professor at UNISON, focusing on biological sciences, particularly in the agri-food field and its connections to public health and the environment. Expanding her research internationally, she became an Associate Researcher at the University of Arizona’s Department of Environmental Sciences from 2021 to 2022. She continued her work there as a Visiting Professor with a Research Scholar position from 2023 to 2024 and is currently an Associate Researcher (2024-2025). Her research at the University of Arizona focuses on the innovation and development of biotechnological products using natural products.

Awards

She has received several distinctions throughout her career, including being recognized as a Distinguished Teacher at the Technological Institute of Sonora in 2006 and 2007. In 2017, she was honored as a Distinguished Citizen in CAJEME by the Interamerican University for Development in Cd. Obregón, Sonora. Her research excellence has been acknowledged by CONACYT’s National System of Researchers, where she was awarded the title of National Researcher Level C from January 1, 2016, to December 31, 2018. She advanced to National Researcher Level 1 in the area of Agricultural, Livestock, Forestry, and Ecosystem Sciences from 2019 to 2021 and continued at Level 1 in the area of Biotechnology and Agricultural Sciences for the period from January 1, 2021, to December 31, 2026.

Research Experience

She has extensive experience in research and development, demonstrating expertise in implementing technologies and innovative practices to enhance agricultural productivity, food security, and environmental sustainability. Her work focuses on utilizing scientific and technological tools to address complex challenges in the agri-food sector.

She completed a postdoctoral fellowship at the National Laboratory for Research in Food Safety (LANNIA), CONACYT, at the Center for Research in Food and Development (CIAD) (2016-2017), where she worked on the chemical and biological characterization of agro-industry products. Her research experience includes multiple research stays at CIAD: in 2004 at the Environmental Microbiology Laboratory (Culiacán Unit, Sinaloa), where she developed her master’s thesis on disinfection applications in mango products; in 2012 at the Antioxidant Laboratory (Hermosillo Unit, Sonora), where she evaluated the antioxidant capacities of agro-industrial products; and in 2013 at the Environmental Microbiology Laboratory (Culiacán Unit, Sinaloa), where she conducted her doctoral research on the characterization of antiviral studies of agro-industrial products.

Additionally, in 2016, she conducted a research stay at the Autonomous University of Mexico (UNAM), working at the Center for Genomic Sciences (CCG) in Cuernavaca, Morelos, focusing on the genomic characterization of bacteriophages isolated from agricultural valleys in Southern Sonora, Mexico.

Publication