Ms. Anett Hudák | Neurodegeneration | Women Researcher Award

Anett Hudák is a skilled molecular biologist with deep expertise in neurobiology, virology, and molecular pathology. She earned her MSc in Molecular Biology from the University of Debrecen with a specialization in biomedical sciences and pharmacology. Over the years, she has significantly contributed to the understanding of cellular communication, amyloid pathology, and viral entry mechanisms through her work on syndecans. With professional experience spanning academia and industry, Anett currently serves as a molecular biologist at Pharmacoidea Ltd., where she leads impactful research on Alzheimer’s disease, SARS-CoV-2, and neurodegeneration. Her publications in high-impact journals like Scientific Reports and International Journal of Molecular Sciences reflect her strong research acumen. Anett’s extensive training in laboratory techniques, radiation protection, and animal experimentation, along with her dedication and collaborative mindset, make her a valued asset in translational biomedical research. She continues to drive discovery at the intersection of molecular biology and therapeutic innovation.

Profile

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🎓 Education

Anett Hudák began her academic journey at Benka Gyula Lutheran Primary School and graduated from Andrássy Gyula Secondary School. She completed her BSc in Biology with a specialization in Laboratory Operations at the University of Debrecen’s Faculty of Science and Technology. She further pursued an MSc in Molecular Biology at the University of Debrecen’s Faculty of Medicine, specializing in Biomedical Sciences and Pharmacology. During her studies, she also received extended-level radiation protection training from the University of Debrecen’s Radiation Protection Service. Anett later earned a Certification in Laboratory Animal Science from the Institutional Animal Welfare Committee at Semmelweis University. Her academic formation has been enriched by intensive hands-on research training in various biomedical techniques including PCR, genotyping, electrophoresis, immunohistochemistry, and animal experimentation. This solid educational background has laid the groundwork for her successful transition into a career in academic and industrial molecular biology research.

🧪 Experience

Anett Hudák has a rich portfolio of research and laboratory experience, beginning with her early work on HPV detection in cervical cancer diagnostics at the Institute of Medical Microbiology, University of Debrecen. She expanded her expertise during her research internship at the Department of Anatomy, Histology and Embryology, where she investigated IL-1RI’s role in inflammatory pain models. From 2012 to 2014, she gained proficiency in cell biology techniques including immunofluorescence and Western blotting. She worked as a laboratory biologist at the Institute of Physiology, Semmelweis University (2015–2016), contributing to studies on lymphangiogenesis in embryonic development. Since 2016, she has been a molecular biologist at Pharmacoidea Ltd., conducting translational research on syndecans in viral transmission, amyloid aggregation, and neurodegenerative diseases. Her contributions to scientific conferences and collaborative publications demonstrate her ability to lead and participate in high-impact research projects that bridge molecular science and therapeutic development.

🏅 Awards and Honors

While formal awards are not extensively listed in Anett Hudák’s CV, her achievements are evident through her selection for prominent speaking roles and poster presentations at respected conferences such as the Pannonia Congress of Pathology (2014), MÉT 2015, and FAMÉ 2016. Her research has consistently been showcased in these forums, highlighting its relevance and impact. Furthermore, Anett’s work has resulted in numerous peer-reviewed publications in top-tier journals like Scientific Reports and International Journal of Molecular Sciences, indicating recognition by the scientific community. Her collaborative publications with international experts, such as Martin Hofmann-Apitius and Mimoun Azzouz, underscore her respected standing in biomedical research. Anett’s ability to lead first-author publications and contribute significantly to multi-author research reflects a level of distinction that is often synonymous with academic honors. Her rising trajectory in neurodegenerative and virology research suggests she is well-positioned for future scientific accolades and leadership roles.

🔬 Research Focus

Anett Hudák’s research centers on the role of syndecans in cellular communication, neurodegenerative disease pathology, and viral entry mechanisms. Her work has significantly contributed to understanding how these membrane proteins facilitate the internalization and aggregation of amyloid-β, α-synuclein, and tau—key proteins involved in Alzheimer’s and Parkinson’s diseases. She also explores how syndecans enable SARS-CoV-2 entry, including variants like Delta and Omicron, offering insights into COVID-19 pathogenesis and therapeutic intervention. Recent studies delve into the interaction between apolipoproteins and syndecans and how these pathways impact cellular events relevant to amyloid disorders. Her use of tissue decolorization, single-cell resolution imaging, and endocytosis analysis has positioned her research at the forefront of molecular neuroscience and virology. Anett’s interdisciplinary approach, spanning molecular biology, cell signaling, and pathology, not only addresses fundamental mechanisms but also aims to inform novel therapeutic strategies for infectious and neurodegenerative diseases.

✅ Conclusion

Anett Hudák is a dedicated and impactful molecular biologist whose research on syndecans, neurodegeneration, and viral entry has advanced both basic science and translational applications in biomedicine.

Publications

• Contribution of syndecans to cellular uptake and fibrillation of α-synuclein and tau
  A Hudák, E Kusz, I Domonkos, K Jósvay, AT Kodamullil, L Szilák, …
  Scientific Reports 9 (1), 16543
• Contribution of syndecans to the cellular entry of SARS-CoV-2
  A Hudak, A Letoha, L Szilak, T Letoha
  International journal of molecular sciences 22 (10), 5336
• Contribution of syndecans to cellular internalization and fibrillation of amyloid-β (1–42)
  T Letoha, A Hudák, E Kusz, A Pettkó-Szandtner, I Domonkos, K Jósvay, …
  Scientific reports 9 (1), 1393
• Syndecan-3 as a novel biomarker in Alzheimer’s disease
  A Hudák, A Letoha, C Vizler, T Letoha
  International Journal of Molecular Sciences 23 (6), 3407
• Syndecan-4 is a key facilitator of the SARS-CoV-2 delta variant’s superior transmission
  A Hudák, G Veres, A Letoha, L Szilák, T Letoha
  International Journal of Molecular Sciences 23 (2), 796
• The interplay of apoes with syndecans in influencing key cellular events of amyloid pathology
  A Hudák, K Jósvay, I Domonkos, A Letoha, L Szilák, T Letoha
  International journal of molecular sciences 22 (13), 7070