Alaa Abd-Elsayed | Neuromidulation | Best Researcher Award

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Dr. Alaa Abd-Elsayed | Neuromidulation | Best Researcher Award

Dr. Alaa Abd-Elsayed ๐Ÿ‡บ๐Ÿ‡ธ is an American board-certified anesthesiologist and pain medicine specialist at the University of Wisconsin-Madison ๐Ÿฅ, recognized for his leadership, groundbreaking research ๐Ÿ”ฌ, and compassionate patient care ๐Ÿ’‰, with a prolific academic career as a professor, director, and global speaker ๐ŸŽค, blending clinical excellence, innovation, and education ๐Ÿ“š in pain management, with over two decades of medical service and leadership roles across Egypt ๐Ÿ‡ช๐Ÿ‡ฌ and the U.S. ๐Ÿ‡บ๐Ÿ‡ธ, while holding numerous prestigious certifications ๐Ÿ…, published research, and leadership awards ๐Ÿ†, he stands as a dedicated pioneer in improving chronic pain therapy ๐Ÿ”ฅ and anesthesiology practice worldwide ๐ŸŒ.

Profile

Education ๐ŸŽ“

Dr. Alaaโ€™s academic journey began at Assuit University ๐Ÿ‡ช๐Ÿ‡ฌ, earning his MBBCh ๐Ÿฉบ in 2000 & MPH ๐ŸŽ“ in 2006; postgrad, he trained extensively in the U.S. ๐Ÿ‡บ๐Ÿ‡ธ, completing internships, anesthesiology residency, and a pain medicine fellowship ๐Ÿฅ at the University of Cincinnati ๐ŸŽฏ, and a Clinical Research Fellowship at Cleveland Clinic ๐Ÿงช; board-certified in anesthesiology & chronic pain medicine ๐Ÿ’Š, and a Certified Physician Executive (CPE) ๐Ÿ†, he capped his academic prowess with an Executive MBA ๐ŸŽ“ in 2023, mastering both medicine & healthcare leadership ๐Ÿง , and attending diverse leadership programs ๐Ÿ’ผ from AAPL, UW Health, and Faulkner University, cementing a strong foundation in clinical care and strategic innovation โšก.

Experience ๐Ÿ‘จโ€๐Ÿซ

With over 20 years in medicine ๐Ÿฉบ, Dr. Alaa has held roles from intern ๐Ÿ‘จโ€โš•๏ธ in Egypt ๐Ÿ‡ช๐Ÿ‡ฌ to Associate Professor ๐Ÿ“–, First Division Chief, and Medical Director at UW-Madison ๐Ÿ‡บ๐Ÿ‡ธ; he’s led UW Health Pain Services ๐Ÿ”ฅ, pioneering chronic pain medicine management ๐Ÿ’Š; his journey spanned positions at Assuit University, Cleveland Clinic, and University of Cincinnati ๐Ÿฅ; heโ€™s served as chief fellow, staff anesthesiologist, researcher ๐Ÿ”ฌ, educator ๐Ÿ“š, and leader, combining advanced clinical practice ๐Ÿ† with administrative excellence ๐Ÿ’ผ, mentoring future physicians while driving cutting-edge research ๐Ÿš€ and pain medicine innovations ๐ŸŒŸ.

Awards & Recognitions ๐Ÿ…

Dr. Alaaโ€™s distinguished career is crowned with awards ๐ŸŒŸ like the Raj/Racz Excellence Award ๐Ÿฅ‡, Physician of the Year ๐Ÿ…, Americaโ€™s Top Doctors ๐Ÿ‘, Fellow of ASA ๐Ÿง , and recognition as a World Expert ๐ŸŒ in pain by Expertscape; multiple top research, poster ๐Ÿ–ผ๏ธ, and abstract prizes ๐Ÿงพ from ASIPP, MARC, ASPN, ASA, INS & WSA ๐Ÿ† highlight his prolific contributions, while his books ๐Ÿ“š were ranked among the best in anesthesiology and pain medicine ๐Ÿ’Š; his research has shaped clinical practices ๐ŸŒก๏ธ and his leadership has been applauded across national and global stages ๐ŸŽค, underlining his impact as a clinician, educator, and thought leader ๐Ÿ’ก.

Research Interests ๐Ÿ”ฌ

Dr. Alaaโ€™s research explores pain management innovation ๐Ÿ”ฅ, neuromodulation โšก, spinal cord stimulation ๐Ÿง , dorsal root ganglion therapies ๐Ÿ’‰, and anesthesiology outcomes ๐Ÿงพ; heโ€™s passionate about translating bench-to-bedside discoveries ๐Ÿฅ, optimizing patient-centered chronic pain therapies ๐Ÿ’Š, and advancing perioperative safety ๐ŸŒก๏ธ; his peer-reviewed publications ๐Ÿ“š, clinical trials ๐Ÿงช, and systematic reviews โš—๏ธ have influenced global practices ๐ŸŒ, securing his place among top 0.05% scholars worldwide ๐Ÿ†; his scientific vision combines clinical evidence, bioethics, and real-world health solutions for pain relief and anesthetic care ๐Ÿง ๐Ÿ’ก.

Publicationsย 

Wei Jiang | Cognitive and neuropathology | Women Researcher Award

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ย Dr. Wei Jiang | Cognitive and neuropathology | Women Researcher Award

Medical University of South Carolina , United States

Her academic focus includes microbiome, B cell/autoantibody interactions, and disease pathogenesis, with particular emphasis on HIV, addictive drugs, and systemic lupus erythematosus (SLE). She is involved in several clinical and translational research projects, including R01DA059854 (Jiang & Sheng), investigating the impacts of drug abuse on autoantibodies and immune reconstitution in HIV. She also works on CSRD Merit I01 CX002422, exploring B cell-mediated immunological failure in HIV-infected individuals on antiretroviral therapy. Additionally, she contributes to NIDA-funded studies, such as R01DA055523, examining the oral microbiome’s effect on cognition in HIV-infected cannabis users, and R01DA059538, investigating HIV persistence in cocaine users. Furthermore, she collaborates on a Translational Science Award project exploring the oral microbiome’s impact on cognition in Alzheimer’s disease.

 

 

Profile

Education:

She earned her M.S. in Epidemiology and Biostatistics from Case Western Reserve University, Medical School, Cleveland, USA, in 2012. Prior to that, she completed a Postdoctoral fellowship at Case Western Reserve University, Medical School, Cleveland, USA, in 2008. She holds an M.S. in Immunology from Capital Medical University, Beijing, China, which she completed in 2001. She also received her M.D. in Internal Medicine from Capital Medical University, Beijing, China, in 1997.

BRIEF RESEARCH INTEREST STATEMENT:

She has 8 years of clinical experience in infectious diseases and 22 years of translational research experience in disease immunopathogenesis. As a corresponding author, she has published 52 peer-reviewed articles on microbiome and disease immunopathogenesis in high-profile journals like Microbiome, Arthritis & Rheumatology, J Autoimmunity, and EbioMedicine, bringing her total number of peer-reviewed publications to 101. As a physician-scientist, she has served as Principal Investigator on five R01 grants from NIAID or NIDA, along with a VA clinical merit grant, focusing on microbiomes, drug abuse, autoimmunity, and HIV immunopathogenesis. Her research primarily focuses on two major areas. The first is understanding the role of B cell perturbation and autoantibodies in disease pathogenesis, particularly in HIV and SLE. In 2017, her team first determined that autoimmunity impacts antiretroviral therapy outcomes in HIV without inducing autoimmune disease. This concept was later corroborated in studies on COVID-19. Her team is currently developing monoclonal autoantibodies and inhibitors to prevent anti-CD4 autoantibody binding, aiming to improve CD4+ T cell recovery and reduce morbidity in HIV patients. The second area of focus is the role of microbiomes in disease pathogenesis, including HIV, SLE, and drug abuse. She has identified the impact of disease-associated pathobionts on immune perturbations and disease progression, with findings validated in animal models. Her microbiome research is supported by R01DA055523.

TRAINING, PROFESSIONAL APPOINTMENTS

She currently serves on the Appointment, Promotion & Tenure (APT) committee in the Department of Microbiology and Immunology at the Medical University of South Carolina, a position she has held since 2024. She was promoted to Full Professor with tenure in the Department of Microbiology and Immunology, Division of Infectious Diseases, Department of Medicine at the same institution in 2023. She has been a Faculty Senator for the College of Medicine and a Research Health Scientist at the Ralph H. Johnson VA Medical Center since 2022. Additionally, she is a member of the Translational Science Laboratory IAC (2020-2022) and the MUSC Collegeโ€™s Curriculum Committee (2019-Present). She has held various positions at MUSC, including Associate Professor (2018-2022) and Assistant Professor (2012-2018) in the Department of Microbiology and Immunology. Since 2018, she has been a member of the Hollings Cancer Center at MUSC and has served on the award committee for the Advancement, Recruitment, and Retention of Women in Science. Her academic career began as an Instructor (2008-2012) and Research Associate (2002-2008) at Case Western Reserve University School of Medicine in Cleveland, OH.

AWARDS

She received her Chinese Board of Internal Medicine certification in Infectious Diseases in July 1997 and was certified as an Attending Medical Doctor in Infectious Diseases in November 1999 (No: 10203C089758). In July 1997, she also earned a Teacher Qualification from the Educational Institute, National Educational Committee in China (No: 971100071069382). Her licensure is from Beijing, China.

She has received several awards throughout her career, including the Laboratory Travel Grant from the American Association of Immunologists (AAI) in 2019, the MUSC High Impact Research Publication Award in 2019, and multiple travel grants from AAI for various international immunology congresses. She was awarded the Early Career Faculty Travel Grant by AAI and ECI in 2018 and 2017, and received the Travel Award and HIV Section Chair recognition at the 2016 International Congress of Immunology. In 2015, she was honored with the MUSC Foundation Developing Scholar Award and an Early Career Faculty Travel Grant from AAI. Her earlier achievements include multiple Young Investigator Awards from the 13th and 15th Conferences on Retroviruses and Opportunistic Infections (2006, 2008) and the Keystone Meeting on HIV Pathogenesis (2006, 2008). Additionally, she was recognized as an Outstanding Student Leader for five consecutive years during her medical school years from 1986 to 1991.

OTHER EXPERIENCE AND PROFESSIONAL MEMBERSHIPS

She has held several key professional roles and memberships throughout her career. Since 2024, she has been serving as a mentor for the American Society for Microbiology (ASM) Future Leaders Mentorship Fellowship (FLMF) Program. She is a member of the Society on NeuroImmune Pharmacology 2024 committee and has been a Treasurer Elect for the Association of Chinese Virologists in America from 2022 to 2024. She has been a member of the American Society for Microbiology (ASM) since 2021 and the Infectious Diseases Society of America (IDSA) since 2020. She has also been serving on the Editorial Board of the Journal of Neuroimmune Pharmacology since 2019 and is a member of the Society on NeuroImmune Pharmacology. Additionally, she has been part of the Society of Chinese Bioscientists in America (SCBA) and the American College of Rheumatology since 2018. She has contributed as an award committee member for the Advancement, Recruitment, and Retention of Women in Science at the Medical University of South Carolina since 2017 and is an associate member of the Hollings Cancer Center at MUSC.

She is also an active member of the MUSC Oral Health Center, College of Dental Medicine, and the Medical University of South Carolina College of Graduate Studies. Her previous memberships include being part of the American Association of Immunologists from 2011 to 2021, the Center for AIDS Research from 2008 to 2012, and the AIDS Clinic Trial Group since 2008. Her certification in Chinese Board of Internal Medicine in Infectious Diseases dates back to 1997, along with her teacher qualification from the Educational Institute, National Educational Committee, China.

CURRENT RESEARCH PROJECTS

She is currently leading several impactful research projects. As the Principal Investigator (PI) on R01DA059854 (9/30/2024-5/31/2029), funded by NIDA with a total of $3,924,302, she is studying the impacts of drug abuse-mediated inflammatory perturbations on affinity maturation of anti-CD4 autoantibodies and poor immune reconstitution from ART in HIV. This project aims to understand the role of cocaine in autoimmunity and immune recovery in HIV patients. Her role in this project is as PI (25% effort).

She is also a multiPI on R01DA059538 (9/30/2023-7/31/2028), with a total of $1,724,585 from NIDA, investigating host gene isoforms contributing to HIV persistence in cocaine users. The study focuses on identifying gene isoforms associated with HIV infection in elite controllers and its implications for cocaine users. Her role is PI (25% effort).

In addition, she is the PI on I01CX002422 (3/1/2022-2/28/2026), funded by the VA Medical Center CSRD Merit with a total of $1,195,899. This project examines the mechanism of autoreactive B cell-mediated immunological failure in HIV-infected individuals on antiretroviral therapy despite virologic suppression. She is focused on understanding the molecular mechanisms of anti-CD4 IgG-producing B cells and the pathologic effects of anti-CD4 autoantibodies. Her role is PI with 62.5% effort.

Additionally, she is involved as multiPI on R01DA055523 (9/30/2022-7/31/2027), with a total funding of $1,731,992, where she is working alongside Fitting to investigate the effects of microbiome-related mechanisms on H

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