Toshifumi Ohkusa is a distinguished physician-scientist with extensive expertise in gastroenterology, internal medicine, and microbiota research. He completed his medical education at Tokyo Medical and Dental University, earning both an MD and a PhD with research focused on experimental ulcerative colitis and intestinal microflora. His professional career spans roles as Research Associate, Instructor, Assistant Professor, and Associate Professor, later advancing to Professor in the Department of Gastroenterology and Hepatology at The Jikei University Kashiwa Hospital, before becoming a Special Professor at the Department of Microbiota Research at Juntendo University Graduate School of Medicine. His academic journey also includes service as a visiting professor, reflecting his broad influence in clinical and translational research. His research interests center on inflammatory bowel disease, intestinal microbiota, gastrointestinal infections, and the pathophysiology of ulcerative colitis. Skilled in clinical studies, microbiota analysis, endoscopy, and translational approaches, he has contributed significantly to the understanding of intestinal health and disease. He is a fellow and active member of numerous national and international professional societies, and he serves as an editor and associate editor for respected journals in gastroenterology, microbiology, and nutrition. His honors and memberships highlight his leadership and recognition in advancing gastroenterological science. In conclusion, Dr. Ohkusa’s career reflects a lifelong dedication to medical research, clinical excellence, and academic mentorship, establishing him as a prominent authority in gastroenterology and microbiota research.
Okayasu, I., Hatakeyama, S., Yamada, M., Ohkusa, T., Inagaki, Y., & Nakaya, R. (1990). A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology, 98(3), 694–702. Cited by: 3209
Andreyev, H. J. N., Norman, A. R., Cunningham, D., Oates, J., Dix, B. R., et al. (2001). Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study. British Journal of Cancer, 85(5), 692–696. Cited by: 1135
Ohkusa, T., Koido, S., Nishikawa, Y., & Sato, N. (2019). Gut microbiota and chronic constipation: A review and update. Frontiers in Medicine, 6, 19. Cited by: 380
Ohkusa, T., Okayasu, I., Ogihara, T., Morita, K., Ogawa, M., & Sato, N. (2003). Induction of experimental ulcerative colitis by Fusobacterium varium isolated from colonic mucosa of patients with ulcerative colitis. Gut, 52(1), 79–83.
Cited by: 367
Koido, S., Ohkusa, T., Homma, S., Namiki, Y., Takakura, K., Saito, K., Ito, Z., et al. (2013). Immunotherapy for colorectal cancer. World Journal of Gastroenterology, 19(46), 8531–8542. Cited by: 365
Ohkusa, T., Fujiki, K., Takashimizu, I., Kumagai, J., Tanizawa, T., Eishi, Y., et al. (2001). Improvement in atrophic gastritis and intestinal metaplasia in patients in whom Helicobacter pylori was eradicated. Annals of Internal Medicine, 134(5), 380–386. Cited by: 315
Ohkusa, T., Sato, N., Ogihara, T., Morita, K., Ogawa, M., & Okayasu, I. (2002). Fusobacterium varium localized in the colonic mucosa of patients with ulcerative colitis stimulates species-specific antibody. Journal of Gastroenterology and Hepatology, 17(8), 849–853. Cited by: 276
Okayasu, I., Ohkusa, T., Kajiura, K., Kanno, J., & Sakamoto, S. (1996). Promotion of colorectal neoplasia in experimental murine ulcerative colitis. Gut, 39(1), 87–92. Cited by: 274