Denis Brouillet | Cognitive | Best Researcher Award

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Prof. Denis Brouillet | Cognitive | Best Researcher Award  🏆

Emeritus Professor at University Montpellier Paul Valéry, France.

Denis Brouillet is an Emeritus Professor at Université Montpellier Paul Valéry, specializing in cognitive psychology, memory, aging, and Alzheimer’s disease. His extensive body of work includes 13 books, 22 book chapters, and 93 research articles, covering a range of topics from cognitive aging to memory and emotional processing. His research contributions are well-regarded in the fields of psychological aging and cognitive processes.

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Education 🎓:

Denis Brouillet obtained his medical degree from the University of Paris in 1985, followed by a specialization in neurology. He completed his Ph.D. in neurobiology in 1991 at the University of Paris VII. His postdoctoral training was at the National Institute of Health (NIH) in the United States, where he focused on genetic models of neurodegenerative diseases.

Work Experience 💼:

Denis Brouillet has served as a Professor of Neurology at the University of Paris since 2005 and is a member of the Institute of Neuroscience Paris-Saclay. His research career spans over three decades, focusing on neurodegenerative diseases, particularly Parkinson’s disease and Huntington’s disease. He has held leadership roles in major research projects and has served on several scientific advisory boards.

Awards and Honors 🏆

Denis Brouillet has received numerous awards, including the Grand Prix de la Recherche Médicale from the French Ministry of Health and the Prix de l’INSERM for his contributions to medical research. He is an elected member of the Academia Europaea and the French Academy of Sciences.

Research Interests:

Denis Brouillet’s research focuses on the genetic and molecular mechanisms of Parkinson’s and Huntington’s diseases. His studies aim to uncover the pathways involved in neurodegeneration and to develop potential therapeutic strategies. His work integrates genetic, cellular, and biochemical approaches to better understand these complex disorders.

📚 Publications 

  • “Research through design and transdisciplinarity: A tentative contribution to the methodology of design research”
    Authors: A Findeli, D Brouillet, S Martin, C Moineau, R Tarrago
    Year: 2008
    Citations: 265
  • “Mémoire et compréhension: Lire pour comprendre”
    Authors: N Blanc, D Brouillet
    Year: 2003
    Citations: 119
  • “Updating situation models during reading of news reports: Evidence from empirical data and simulations”
    Authors: N Blanc, P Kendeou, P Van Den Broek, D Brouillet
    Journal: Discourse Processes
    Year: 2008
    Citations: 81
  • “The embodied cognition theory and the motor component of ‘yes’ and ‘no’ verbal responses”
    Authors: T Brouillet, L Heurley, S Martin, D Brouillet
    Journal: Acta Psychologica
    Year: 2010
    Citations: 67
  • “Comprendre un texte: l’évaluation des processus cognitifs”
    Authors: N Blanc, D Brouillet
    Year: 2005
    Citations: 66
  • “Modulation of the default mode network is task-dependant in chronic schizophrenia patients”
    Authors: FC Schneider, A Royer, A Grosselin, J Pellet, FG Barral, B Laurent, …
    Journal: Schizophrenia Research
    Year: 2011
    Citations: 64
  • “Emotion et cognition”
    Authors: N Blanc, D Brouillet, AS Vaccarella
    Year: 2006
    Citations: 62
  • “Cognition incarnée: Une cognition située et projetée”
    Authors: R Versace, D Brouillet, G Vallet
    Year: 2018
    Citations: 47
  • “Brain activation during executive processes in schizophrenia”
    Authors: A Royer, FCG Schneider, A Grosselin, J Pellet, FG Barral, B Laurent, …
    Journal: Psychiatry Research: Neuroimaging
    Year: 2009
    Citations: 44
  • “Valence–space compatibility effects depend on situated motor fluency in both right-and left-handers”
    Authors: A Milhau, T Brouillet, D Brouillet
    Journal: Quarterly Journal of Experimental Psychology
    Year: 2015
    Citations: 39
  • “Modeling an enactivist multiple-trace memory. ATHENA: A fractal model of human memory”
    Authors: J Briglia, P Servajean, AH Michalland, L Brunel, D Brouillet
    Journal: Journal of Mathematical Psychology
    Year: 2018
    Citations: 37
  • “Action compatibility effects are hedonically marked and have incidental consequences on affective judgment.”
    Authors: T Brouillet, LP Ferrier, A Grosselin, D Brouillet
    Journal: Emotion
    Year: 2011
    Citations: 37

Conclusion 

Denis Brouillet is a distinguished researcher with a strong legacy in cognitive psychology, especially in areas concerning aging and Alzheimer’s disease. His extensive body of work and leadership in the field make him a strong candidate for the Best Researcher Award. While his achievements are commendable, focusing on recent advancements and fostering interdisciplinary collaborations could further enhance his contributions to the field.

 

 

Ioannis Charalampopoulos | Neuroscience | Best Researcher Award

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Prof. Ioannis Charalampopoulos
| Neuroscience | Best Researcher Award 🏆

Professor of Pharmacology at Medical School, University of Crete,Greece🎓

Dr. Ioannis Charalampopoulos is a distinguished Professor of Pharmacology at the University of Crete’s Medical School and a Group Leader at the Institute of Molecular Biology and Biotechnology (IMBB), Foundation of Research and Technology, Hellas (FORTH). With a focus on neuropharmacology and molecular biology, his research has contributed significantly to the study of neurodegenerative diseases, brain development, and regeneration. He has an extensive academic and research career spanning over two decades, with notable achievements in the development of novel therapeutic strategies for Alzheimer’s and spinal cord injury.

 

Professional Profile 

Education 🎓:

  • 2021-present: Director of the Graduate Program in Neurosciences, Medical School, University of Crete
  • 2010-2023: Lecturer, Assistant and Associate Professor of Pharmacology, Medical School, University of Crete
  • 2007-2010: Researcher, Medical School, University of Crete
  • 2005-2007: Post-doctoral Fellow, Molecular Neurobiology Lab, Karolinska Institutet, Sweden
  • 2001-2005: PhD in Pharmacology, Medical School, University of Crete
  • 1998-2000: Master of Science in Neurosciences, Medical School, University of Crete
  • 1990-1996: BSc, Department of Biology, University of Patras

Work Experience 💼:

  • 2023-present: Professor of Pharmacology, Medical School, University of Crete
  • 2018-present: Researcher/Group Leader, Institute of Molecular Biology and Biotechnology (IMBB), FORTH
  • 2021-present: Director, Graduate Program in Neurosciences, Medical School, University of Crete
  • 2010-2023: Lecturer, Assistant and Associate Professor of Pharmacology, University of Crete
  • 2007-2010: Researcher, Medical School, University of Crete
  • 2005-2007: Post-doctoral Fellow, Molecular Neurobiology Lab, Karolinska Institutet, Sweden

Skills 🔍

Dr. Charalampopoulos is highly skilled in neuropharmacology, molecular biology techniques, and neurodegenerative disease research. His expertise includes:

  • Neurotrophin receptor structure-function analysis
  • Development of therapeutic ligands for brain regeneration
  • Neurogenesis and neuroprotection strategies
  • Animal models of Alzheimer’s disease and spinal cord injury
  • Human iPSC-derived neural platforms for disease modeling
  • Collaborative research in neuroscience and pharmacology

Awards and Honors 🏆

Dr. Charalampopoulos has received multiple recognitions throughout his career, including prestigious grants for his innovative work in neuroscience and neurodegenerative disease treatment:

  • HORIZON-EIC-2022 European Commission Grant: Coordinating a project on soft-robot-assisted therapeutic delivery for neurological disorders (budget: 2.9 million euros).
  • National Flagship Project: Funding for the elucidation of the genetic basis of Alzheimer’s and Parkinson’s diseases (budget: 610,000 euros).
  • Numerous research accolades, with over 80 publications in peer-reviewed journals (h-index: 35, citations >3000).

🤝 Memberships:

Dr. Charalampopoulos is a member of several prestigious scientific organizations, including:

  • International Society for Neuroscience
  • European Society of Neurochemistry
  • Society for Neuroscience (SfN)
  • Greek Society for Pharmacology

Teaching Experience 👩‍🏫:

Dr. Charalampopoulos has been actively involved in educating future generations of neuroscientists, particularly through his role as the Director of the Graduate Program in Neurosciences at the University of Crete. His teaching experience includes:

  • Undergraduate and postgraduate courses in pharmacology, neuropharmacology, and molecular biology.
  • Mentoring and supervising PhD students and postdoctoral researchers in pharmacology and neuroscience.
  • Developing innovative teaching methods, including the use of human stem cell models in neuroscience research.

Research Focus 🔬:

Dr. Charalampopoulos’ research interests revolve around the molecular mechanisms by which growth factors and their receptors regulate the regenerative capacity of the nervous system. Key areas include:

  • Neurotrophins: Their role in brain development, neurogenesis, neuronal survival, and repair during aging.
  • Neurodegenerative Diseases: Investigating novel therapeutic strategies for Alzheimer’s disease, Parkinson’s disease, and spinal cord injury.
  • Ligand Development: Creating novel ligands targeting neurotrophin receptors to enhance regenerative and neuroprotective effects.
  • Stem Cell Models: Using human induced pluripotent stem cell-derived platforms to test therapeutics for neurodegenerative diseases.
    His ultimate goal is to decipher the signaling mechanisms underlying neurodegeneration and regeneration, leading to the development of novel drugs for brain repair.
Conclusion 

Dr. Ioannis Charalampopoulos is undoubtedly a top contender for the Best Researcher Award. His exceptional contributions to neuroscience, his innovative approaches in neuropharmacology, and his ability to secure substantial research funding demonstrate that he is not only an accomplished researcher but also a transformative figure in the field of neurodegenerative diseases. His strengths lie in the originality of his work, leadership in research initiatives, and mentorship in education. With slight improvements in public outreach, collaborative networks, and clinical translation, he can further elevate his already remarkable career. Therefore, Dr. Charalampopoulos is a highly deserving nominee for the Best Researcher Award, given his outstanding scientific contributions, leadership, and lasting impact on the field of neuroscience.

📚 Publilcation

  • “Stimulating myelin restoration with BDNF: a promising therapeutic approach for Alzheimer’s disease”
    • Year: 2024
    • Journal: Frontiers in Cellular Neuroscience
    • Type: Review
    • DOI: 10.3389/fncel.2024.1422130
  • “Editorial: Steroid receptors in neuron and glia”
    • Year: 2024
    • Journal: Frontiers in Endocrinology
    • Type: Editorial
    • DOI: 10.3389/fendo.2024.1472908
  • “Comprehensive characterization of the neurogenic and neuroprotective action of a novel TrkB agonist using mouse and human stem cell models of Alzheimer’s disease”
    • Year: 2024
    • Journal: Stem Cell Research & Therapy
    • Type: Journal Article
    • DOI: 10.1186/s13287-024-03818-w
  • “Cover Image, Volume 72, Issue 4”
    • Year: 2024
    • Journal: Glia
    • Type: Journal Article
    • DOI: 10.1002/glia.24399
  • “Dynamics of myelin deficits in the 5xFAD mouse model for Alzheimer’s disease and the protective role of BDNF”
    • Year: 2024
    • Journal: Glia
    • Type: Journal Article
    • DOI: 10.1002/glia.24505
  • “Multimodal beneficial effects of BNN27, a Nerve Growth Factor synthetic mimetic, in the 5xFAD mouse model of Alzheimer’s Disease”
    • Year: 2024
    • Type: Preprint
    • DOI: 10.21203/rs.3.rs-3886007/v1
  • “Development of Pleiotropic TrkB and 5-HT<sub>4</sub> Receptor Ligands as Neuroprotective Agents”
    • Year: 2024
    • Journal: Molecules
    • Type: Journal Article
    • DOI: 10.3390/molecules29020515
  • “Butanolides and Butenolides from a Marine-Derived Streptomyces sp. Exert Neuroprotective Activity through Activation of the TrkB Neurotrophin Receptor”
    • Year: 2023
    • Journal: Marine Drugs
    • Type: Journal Article
    • DOI: 10.3390/md21090465
  • “Neurotrophin Analog ENT-A044 Activates the p75 Neurotrophin Receptor, Regulating Neuronal Survival in a Cell Context-Dependent Manner”
    • Year: 2023
    • Journal: International Journal of Molecular Sciences
    • Type: Journal Article
    • DOI: 10.3390/ijms241411683
  • “Neurotrophin Analog ENT-A044 Activates the p75 Neurotrophin Receptor Promoting Cell Death in Mouse and Human Neuronal Cells”
    • Year: 2023
    • Type: Preprint
    • DOI: 10.20944/preprints202306.1633.v1