Adithi Randeni | Transcytosis Mechanisms and Hydrocephalus Pathophysiology | Best Researcher Award

Dr. Adithi Randeni | Transcytosis Mechanisms and Hydrocephalus Pathophysiology | Best Researcher Award

Leeds Teaching Hospitals Trust, United Kingdom

Dr. Randeni A. Adithi H. Randeni is a Foundation Year One doctor at Leeds Teaching Hospital Trust with a dynamic portfolio in clinical research, innovation, and academic leadership. A graduate of the University of Leeds (MBChB), she has gained international exposure through observerships and research collaborations in the UK and USA, including SUNY Upstate. Her scholarly contributions span neurosurgery, cerebrospinal fluid dynamics, and biomedical innovation, with publications in top-tier journals such as IJMS, BJS, and BMC Medical Education. Dr. Randeni has received numerous awards and bursaries and is an active educator and mentor. Her leadership roles in university bodies and national societies reflect her commitment to academic excellence and inclusivity. With a future goal of specializing in neurosurgery, she aims to contribute to translational research and advance surgical practice globally through innovation and collaboration.

Profile

🎓 Education

Dr. Adithi Randeni earned her Bachelor of Medicine and Bachelor of Surgery (MBChB) from the University of Leeds, where she excelled in both academic and research endeavors. Her education was enriched by multiple research projects and electives across the UK and internationally, including SUNY Upstate Medical University in the USA. During her time at Leeds, she engaged deeply with translational research, contributing to projects on hydrocephalus, tissue engineering, neurotrauma, and breast cancer genetics. Her academic training included structured research programs and specialized modules in biomedical innovation, CSF dynamics, and advanced surgical techniques. She also undertook audits, systematic reviews, and service evaluations during clinical placements. Beyond formal education, she participated in national research fellowships and student interest groups that fostered interdisciplinary learning and mentorship. Dr. Randeni’s educational journey reflects a strong integration of clinical knowledge with scientific inquiry, preparing her for a future as a research-driven neurosurgeon and academic leader.

đź§Ş Experience

Dr. Adithi Randeni currently serves as a Foundation Year One doctor at Leeds Teaching Hospital Trust, where she is engaged in hands-on patient care, audits, and quality improvement projects. She has amassed extensive research experience through clinical, translational, and lab-based projects, including those at SUNY Upstate and the University of Leeds. Her past roles include conducting systematic reviews, performing service evaluations in neurosurgery, and leading national student surveys like SMART. She has presented her findings at both national and international conferences and has co-authored peer-reviewed articles and a book chapter. In addition to clinical duties, she has held leadership roles in student organizations, served as a medical student representative, and organized educational workshops. Her involvement with professional societies and interdisciplinary teams highlights her ability to balance clinical work, academic productivity, and collaborative initiatives, making her a well-rounded early-career professional with a clear trajectory in neurosurgical research and innovation.

🏅 Awards and Honors

Dr. Adithi Randeni has been the recipient of numerous academic awards, conference bursaries, and leadership recognitions during her medical training. Her achievements include international presentation opportunities and publication accolades for research on hydrocephalus, surgical outcomes, and student engagement in research pathways. She was invited to co-author a chapter in Springer’s “Arachnoid Cysts: State-of-the-Art” and has contributed to high-impact journals like the British Journal of Surgery and BMC Medical Education. She has earned research travel grants, elective placement scholarships, and teaching recognitions for organizing peer education workshops. Active in student leadership, she received commendations for her roles within the Medical Student Representative Council and societies such as NANSIG and the National MedTech Foundation. Her selection for the “Best Researcher Award” nomination reflects her growing influence in academic medicine. These honors affirm her commitment to excellence in research, innovation, and medical education at an early stage of her professional journey.

🔬 Research Focus

Dr. Adithi Randeni’s research focus lies at the intersection of neurosurgery, cerebrospinal fluid (CSF) dynamics, and biomedical innovation. She has explored pathological mechanisms such as abnormal transcytosis in hydrocephalus, authored a chapter on the genetics of arachnoid cysts, and is actively investigating CSF composition in hydrocephalus through collaborations with SUNY Upstate. Her research interests also include neurotrauma, surgical outcomes, antimicrobial stewardship, and tissue-engineered cardiovascular grafts. With a strong inclination toward translational research, she integrates clinical insights with lab-based findings to drive innovation. Dr. Randeni also explores medical education, having co-led the SMART study on student engagement in research. Her contributions aim to bridge the gap between bedside care and bench science, with ongoing work assessing surgical site infections and diagnostic accuracy in neurosurgical imaging. She is passionate about leveraging biomedical research and digital tools to enhance patient outcomes and surgical practice, particularly in underserved and complex neurological conditions.

âś… Conclusion

Dr. Adithi Randeni exemplifies the fusion of clinical excellence, research innovation, and educational leadership, positioning her as a promising future leader in neurosurgery and translational science.

Publications
  • Abnormal Transcytosis Mechanisms in the Pathogenesis of Hydrocephalus: A Review

    International Journal of Molecular Sciences
    2025-05-19 | Journal article
    Part ofISSN: 1422-0067
    CONTRIBUTORS: Adithi Randeni; Sydney Colvin; Satish Krishnamurthy
  • Genetics of Arachnoid Cysts

    Arachnoid Cysts
    2023 | Book chapter
    Part ofISBN: 9783031227004
    Part ofISBN: 9783031227011
    CONTRIBUTORS: Adithi Randeni; Sydney Colvin; Satish Krishnamurth
  • Cross-sectional Survey of Medical student perceptions of And desires for Research and Training pathways (SMART): an analysis of prospective cohort study of UK medical students

    BMC Medical Education
    2023-12-15 | Journal article
    Part of ISSN: 1472-6920
    CONTRIBUTORS: Gokul Parameswaran; Amelia Bowman; Catherine Swales; Setthasorn Zhi Yang Ooi; Shie Wei Chan; Priya Rose Babu; Daniele Ramsay; Sofia Kostoudi; Soham Bandyopadhyay; SMART-NANSIG-InCiSion Collaborative et al.

Monia Orciani | Stem cells | Best Researcher Award

Prof Dr. Monia Orciani | Stem cells | Best Researcher Award

 

Profile

Education

On January 23, 2004, she was awarded a PhD in Biomedical Biotechnology from the UniversitĂ  Politecnica delle Marche. In 2001, she obtained her qualification as a Professional Biologist from the same institution. She completed her degree in Biological Sciences on March 10, 2000, graduating with top honors (110/110 cum laude).

Her native language is Italian. She is also proficient in English at the C1 level across listening, reading, interaction, speaking, and writing. She achieved the LanguageCert Level 2 Certificate in ESOL International (Speaking) (Expert C1) on January 20, 2023.

Work experience

Since July 15, 2019, she has been serving as an Associate Professor in the scientific-disciplinary sector BIO/17 – Histology at the Department of Clinical and Molecular Sciences, Università Politecnica delle Marche. She obtained her qualification as a Second-Tier Professor in Applied Biology (SSD 05/F1) on April 4, 2017, and later achieved First-Tier Professor qualification in Histology (SSD 05/H2) on November 18, 2020. Previously, she was a confirmed Researcher in Histology at the same department from April 13, 2015, following an initial appointment as a non-confirmed Researcher from November 1, 2011, to April 13, 2015. Before that, she held a research fellowship from June 3, 2011, to November 1, 2011, focusing on the use of stem cells in regenerative medicine. From June 1, 2010, to May 31, 2011, she was a research grant holder investigating skin-derived stem cells and their clinical prospects in regenerative therapy at the Department of Experimental and Clinical Medicine. Between November 1, 2003, and April 15, 2010, she conducted research on leukocyte ectoenzymes and their role in the pathogenesis, diagnosis, and treatment of selected human diseases at the Department of Molecular Pathology and Innovative Therapies – Histology. From July 16, 2001, to July 15, 2003, she held a research fellowship focused on monoclonal antibodies for in vivo applications at the Institute of Biology and Genetics. Her early experience includes an internship at the Institute of Biology, Genetics, and Biochemistry, University of Medicine and Surgery, Turin, from May 1, 2000, to December 1, 2000.

Teaching Experience

Since the academic year 2022/23, she has been the course leader for Histology in the Medicine and Surgery (MedTech) degree programme at the UniversitĂ  Politecnica delle Marche.

Since 2019/20, she has held the position of Histology lecturer within the integrated course Human Morphological Sciences for the Dental Hygiene degree programme at the same university.

She has also taught Histology within the integrated Histology-Anatomy-Physiology course for the Medical Radiology Techniques for Imaging and Radiotherapy degree programme during the academic years 2016/17–2018/19 and again in 2022/23.

Since 2022/23, she has been responsible for teaching Histology within the Morphology and Histology integrated course for the Midwifery degree programme.

Since 2017/18, she has been a Tutor for AFP (Basic Sciences and First Aid Area) in the Medicine and Surgery degree programme.

She has also been involved in structured and cross-disciplinary teaching for the PhD in Human Health and Biomedical Sciences since 2017/18.

Since 2017/18, she has led an elective teaching activity (ADE) titled “Biotechnologies for the Study of Normal Human Histology” in the Medicine and Surgery degree programme.

From 2019/20 to 2021/22, she taught Histology for the Dentistry and Dental Prosthetics degree programme.

Between 2016/17 and 2017/18, she was the English Language course leader for the Medical Radiology Techniques for Imaging and Radiotherapy degree programme.

She is proficient in Microsoft Office and holds an Expert C1 Level LanguageCert Certificate in ESOL International (Speaking), awarded on 20 January 2023.

In the academic year 2018/19, she taught Histology within the Biomedical Sciences 1 integrated course for the Physiotherapy degree programme.

Between 2017/18 and 2018/19, she led a seminar-based Histology course for the Dietetics degree programme.

Since 2016/17, she has been responsible for a seminar-based Histology course in the Nursing degree programme at the Fermo campus.

Between 2012/13 and 2018/19, she taught Histology within the Histology-Anatomy integrated course for the Biomedical Laboratory Techniques degree programme.

Since 2012/13, she has also been responsible for a seminar-based Histology course in the Nursing degree programme at the Macerata campus.

Research project

Professor Monia Orciani has been recognised with the ImmunoTools IT-FlowISiAM-Award 2024 for her research on “Searching for New Targets for Alzheimer’s Disease.” She is the Principal Investigator (PI) of the PRIN 2022 project titled “The Effects of Cortisol Excess on Neurogenesis in Alzheimer’s Disease: A Mandatory Footpath through Stem Cells (FORGETFUL)” (Project ID: 2022XF7XZF). In 2022, she secured funding from Boehringer-Ingelheim for a study on the “Role of Nintedanib on Mesenchymal Stem Cells Derived from Patients with Idiopathic Pulmonary Fibrosis (IPF),” in collaboration with Professor Martina Bonifazi. Additionally, she received the Fondo di Finanziamento AttivitĂ  di Base di Ricerca (FFABR) – FFO grant in 2017 for her research on “Inflammation and Stem Cells: New Associations.” Her work on stem cells also led to a strategic university project (2017–2019) investigating “The Role of Stem Cells in Cutaneous Repair Deficiency in Patients with Endogenous and Exogenous Cushing’s Syndrome.”

Professor Orciani has contributed to several national research initiatives, including PRIN 2017, where she collaborated on “The Impact of Glucocorticoid Circadian Rhythm Disruption on Cardiovascular Risk and Immune Dysfunction: Pathophysiology and Novel Biomarkers of Glucocorticoid Exposure in Hypercortisolism and Hypocortisolism (CHRONO-IMAGE),” led by Professor Rosario Pivonello (Project ID: 2017HRTZYA_005). Earlier in her career, she was involved in FIRB-funded projects, such as the 2011 study on “Molecular Markers for Diagnosis, Prognosis, and the Development of New Therapeutic Strategies for Adrenal Carcinoma” (PI: Professor Roberto Di Primio, Project ID: RBAP1153LS_004) and the 2010 preclinical evaluation of “Scaffolds for Skeletal Tissue Regeneration” (PI: Professor Roberto Giardino, Project ID: RBAP10MLK7_003). In 2010, she participated in a PRIN project examining “The Interaction between Glucose and Bone Metabolism for the Cardiometabolic Characterisation of a Population of Young Obese Individuals” (PI: Professor Roberto Di Primio, Project ID: 201098WFZ2_006). Her involvement in FIRB dates back to 2001, where she contributed to a study on “Leukocyte Ectoenzymes and Their Role in the Pathogenesis, Diagnosis, and Therapy of Selected Human Diseases” (PI: Professor Fabio Malavasi, Project ID: RBNE01N4Z9_003).

Publication

  • 1. Pisciotta A, Di Tinco R, Bertani G, Orlandi G, Bertoni L, Pignatti E, Orciani M, Sena P,
    Bertacchini J, Salvarani C, Carnevale G. Human dental pulp stem cells (hDPSCs) promote the
    lipofibroblast transition in the early stage of a fibro-inflammatory process. Front Cell Dev Biol.
    2023;11:1196023
  • Preziuso A, Piccirillo S, Cerqueni G, Serfilippi T, Terenzi V, Vinciguerra A, Orciani M, Amoroso
    S, Magi S, Lariccia V. Exploring the Role of NCX1 and NCX3 in an In Vitro Model of
    Metabolism Impairment: Potential Neuroprotective Targets for Alzheimer’s Disease. Biology
    (Basel). 2023;12:1005.
  • Di Vincenzo M, Diotallevi F, Piccirillo S, Carnevale G, Offidani A, Campanati A, Orciani M.
    miRNAs, Mesenchymal Stromal Cells and Major Neoplastic and Inflammatory Skin Diseases:
    A Page Being Written: A Systematic Review. Int J Mol Sci. 2023;24:8502.
  • Di Vincenzo M, Orciani M. Special Issue “The Role of Mesenchymal Stem Cells on
    Inflammatory and Fibrotic Diseases”. Int J Mol Sci. 2023;24:8578.
  • Di Vincenzo M, Martino M, Lariccia V, Giancola G, Licini C, Di Benedetto G, Arnaldi G,
    Orciani M. Mesenchymal Stem Cells Exposed to Persistently High Glucocorticoid Levels
    Develop Insulin-Resistance and Altered Lipolysis: A Promising In Vitro Model to Study
    Cushing’s Syndrome. Front Endocrinol (Lausanne). 2022;13:816229