Assist. Prof. Dr. Amir Hossein Zarifkar | Neuroscience | Best Researcher Award

Dr. Zarifkar’s academic journey began with a B.Sc. in Biology from Shiraz University, Iran (2010), where he laid the foundation for his passion in life sciences. He pursued his M.Sc. in Physiology at Ahvaz University of Medical Sciences (2014), conducting a thesis on the protective effects of agmatine in memory impairment models. Building upon this expertise, Dr. Zarifkar earned a Ph.D. in Physiology from Shiraz University of Medical Sciences (2019). His doctoral research, titled “Investigating the effect of transcranial electrical stimulation (tES) paradigms on beta-amyloid-induced memory impairment and hippocampal CA1 structural changes in male rats,” received critical acclaim for its innovative approach to addressing Alzheimer’s disease. Throughout his education, Dr. Zarifkar consistently ranked among the top of his cohort, achieving first rank in the national Ph.D. entrance exam and being honored as a top student at Shiraz University of Medical Sciences.

Work Experience 💼:

Dr. Zarifkar has over a decade of experience in teaching, research, and experimental neurophysiology. As an educator, he delivers comprehensive courses in nervous system, kidney, gastrointestinal, and endocrine physiology to students in medicine, dentistry, pharmacy, and nursing. His hands-on laboratory sessions emphasize practical applications of physiology, fostering a deeper understanding among students. On the research front, Dr. Zarifkar specializes in Alzheimer’s disease, memory impairment, and innovative therapeutic approaches, utilizing advanced methodologies such as transcranial electrical stimulation, immunohistochemistry, and stereotaxic surgery. His expertise extends to conducting behavioral and cognitive experiments in animal models. Dr. Zarifkar’s findings have been presented at national and international conferences, enhancing the global understanding of neurodegenerative diseases. As a member of Iran’s National Elites Foundation, he actively contributes to academic and research communities, solidifying his role as a leader in the field of neurophysiology.

Awards and Honors 🏆

Dr. Zarifkar has received multiple awards and recognitions for his academic excellence and contributions to neuroscience. Notably, he ranked first in the national Ph.D. entrance exam in Physiology, demonstrating his exceptional knowledge in the field. During his M.Sc. and Ph.D. studies, he was honored as a top student at Shiraz University of Medical Sciences. His groundbreaking research on Alzheimer’s disease earned him accolades at national and international scientific conferences. Dr. Zarifkar is also a proud member of Iran’s National Elites Foundation, a prestigious acknowledgment of his academic and research achievements. His dedication to teaching and mentoring has further earned him the respect and admiration of his peers and students alike. These honors reflect Dr. Zarifkar’s unwavering commitment to advancing the field of physiology and contributing to the understanding and treatment of neurodegenerative disorders.

Research Interests:

Dr. Zarifkar’s research centers on understanding the mechanisms underlying neurodegenerative diseases, particularly Alzheimer’s disease, and developing innovative therapeutic strategies. His Ph.D. work investigated the effects of transcranial electrical stimulation (tES) on memory impairment and structural changes in the hippocampus, providing insights into non-invasive treatments for Alzheimer’s. Dr. Zarifkar’s expertise extends to studying the impact of neuroprotective agents like agmatine on cognitive functions and neural plasticity. He employs advanced methodologies, including behavioral and cognitive assessments in animal models, immunohistochemistry, Western blot analysis, and stereotaxic surgery, to unravel the complexities of memory impairment. His findings contribute to a better understanding of the pathophysiology of neurodegenerative disorders and pave the way for potential clinical applications. By bridging experimental neuroscience with translational research, Dr. Zarifkar aims to develop effective interventions for enhancing cognitive health and mitigating the effects of aging-related neurological conditions.

📚 Publications 

Agmatine protects against intracerebroventricular streptozotocin-induced water maze memory deficit, hippocampal apoptosis, and Akt/GSK3β signaling disruption

Authors: M. Moosavi, A.H. Zarifkar, Y. Farbood, M. Dianat, A. Sarkaki, R. Ghasemi

Citations: 46

Year: 2014

Treatment with edaravone improves the structure and functional changes in the hippocampus after chronic cerebral hypoperfusion in rats

Authors: G.H. Meftahi, M. Bayat, A.H. Zarifkar, S. Akbari, A.B. Haghighi, M. Naseh

Citations: 18

Year: 2021

Ameliorative effects of different transcranial electrical stimulation paradigms on the novel object recognition task in a rat model of Alzheimer disease

Authors: A.H. Zarifkar, A. Zarifkar, M. Nami, A. Rafati, H. Aligholi, F. Vafaee

Citations: 12

Year: 2019

Effect of recombinant insulin-like growth factor-2 injected into the hippocampus on memory impairment following hippocampal intracerebral hemorrhage in rats

Authors: F. Vafaee, A. Zarifkar, M. Emamghoreishi, M.R. Namavar, M. Shahpari

Citations: 10

Year: 2018

Interactive Effects of Swimming High-Intensity Interval Training and Resveratrol Supplementation Improve Mitochondrial Protein Levels in the Hippocampus of Aged Rats

Authors: M. Amirazodi, F. Daryanoosh, A. Mehrabi, A. Gaeini, M. Koushkie Jahromi

Citations: 6

Year: 2022

The Comparison of the Effects of Different Transcranial Electrical Stimulation (tES) Paradigms on Beta-Amyloid (Aβ 25–35)-Induced Memory Impairment upon Morris Water Maze Task

Authors: A.H. Zarifkar, A. Zarifkar, M. Nami, A. Rafati, H. Aligholi

Citations: 5

Year: 2018

Different paradigms of transcranial electrical stimulation improve motor function impairment and striatum tissue injuries in the collagenase-induced intracerebral hemorrhage model

Authors: A.R. Heidarzadegan, A. Zarifkar, N. Sotoudeh, M.R. Namavar, A.H. Zarifkar

Citations: 4

Year: 2022

The protective effect of agmatine against intracerebroventricular streptozotocin-induced memory impairment in male rats

Authors: Y. Farbood, A.H. Zarifkar, M. Dianat, A. Sarkaki, M. Moosavi

Citations: 1

Year: 2014

Resistance Training and Resveratrol Supplementation Improve Cancer Cachexia and Tumor Volume in Muscle Tissue of Male Mice Bearing Colon Cancer CT26 Cell Tumors

Authors: M. Samadi, F. Daryanoosh, Z. Mojtahedi, A. Samsamy Pour, H. Nobari

Citations: Not yet cited

Year: 2024

Alterations in FoxO3a, NF-κB, and MuRF1 Expression in the Soleus Muscle of Male Rats Following High-Intensity Interval Training and Detraining

Authors: S. Sheibani, F. Daryanoosh, A.H. Zarifkar

Citations: Not yet cited

Year: 2024

Different paradigms of transcranial electrical stimulation induce structural changes in the CA1 region of the hippocampus in a rat model of Alzheimer’s disease

Authors: A.H. Zarifkar, A. Zarifkar, S. Safaei

Citations: Not yet cited

Year: 2024

P62: Agmatine Protects Against Intracerebroventricular Streptozotocin-Induced Water Maze Memory Deficit, Hippocampal Apoptosis and Akt/GSK3β Signaling Disruption

Authors: M. Moosavi, A.H. Zarifkar, Y. Farbood, M. Dianat, A. Sarkaki, R. Ghasemi

Citations: Not listed

Year: 2018

Conclusion